Fakultäten der Universität Bonn: Suche
Anzeige der Dokumente 131-140 von 142
Validation, determinants and impact of medication use
(2024-04-02)
In recent decades, global medication consumption has increased substantially due to an aging population and more emphasis on preventative treatment. As medication use increases, concerns naturally arise regarding the ...
Establishing blood-based classifiers for decentralized and privacy-preserving disease prediction
(2024-04-08)
Big data is increasingly being generated across all sectors of medicine and high-dimensional omics data have been shown to be a powerful data space for AI applications that can assist in primary and differential diagnostics, ...
Identification of alpha-synuclein and ataxin-3 expression modifying compounds
(2024-02-16)
(noch nicht zugänglich / not yet accessible)
Pilzkontaminationen in Korneatransplantaten: Effektivität antimykotischer Medienzusätze und Anwendbarkeit molekularbiologischer Detektionsmethoden
(2023-10-16)
Postoperative Infektionen stellen eine schwerwiegende Komplikationen nach Korneatransplantation dar. In den letzten Jahren wurde ein Anstieg der Inzidenz von Pilzinfektionen nach Keratoplastik festgestellt. Aktuell werden ...
Impact of aging and enriched environment on α-synuclein propagation
(2022-04-06)
Parkinson's disease (PD) is the second most common neurodegenerative disease. The prevalence of sporadic PD results from a complex interaction of demographic, genetic, and environmental factors. Age is one of the strongest ...
Protein markers of inflammation and ageing in a European multi-centre dementia cohort
(2024-03-01)
Inflammation plays a key role in Alzheimerʼs disease (AD) progression. Microglia in the AD brain are exposed to pathological amyloid β (Aβ42) and tau peptide aggregates, resulting in the NLRP3 inflammasome activation ...
Engagement of NKT cells during cross-priming enhances the CD8+ T cell response via GATA3 and IL-4/TNFα
(2022-04-21)
(noch nicht zugänglich / not yet accessible)
The mesoscale organization of Syntaxin 1A and SNAP25 at the plasma membrane
(2023-03-09)
The plasma membrane is a highly crowded place consisting of a plethora of proteins and lipids, which show a high degree of micropatterning. Most proteins are not homogeneously distributed but concentrated in clusters. ...
The Immune Memory Response and Metabolic Requirements of Human Gamma Delta T Cells
(2024-05-14)
γδ T cells are unconventional T cells that can mediate pro-inflammatory, cytotoxic, phagocytotic and professional antigen presenting properties. Sharing the features of both adaptive and innate immunity, γδ T cells also ...
Activation Mechanisms of RIG-I
(2020-11-02)
(noch nicht zugänglich / not yet accessible)