Faculties of University Bonn: Search
Now showing items 1291-1300 of 1333
GPR183 controls spatial organization and survival of hepatic conventional dendritic cells within hepatic portal regions via M-CSF and Gas6
(2023-04-19)
G protein-coupled receptor 183 (GPR183) recognizes 7α,25-dihydroxycholesterol (7α,25-OHC) and exerts chemotactic action upon recognition. Recent studies have shown that GPR183 is highly expressed in T, B and dendritic cells ...
Neuroanatomie und Funktionsmorphologie Peripherer Rezeptorneurone mit Direkten Projektionen in das Protocerebrum des Insektengehirns
(2023-04-20)
Zur Wahrnehmung unterschiedlicher thermischer Reize hat sich bei Insekten eine Reihe von Thermorezeptoren entwickelt. Der pyrophile („feuerliebend“) „Australische Feuerkäfer“ (Merimna atrata) besitzt paarige Infrarot-(IR)-Organe ......
Ectopic expression of transcription factors to overcome the lineage barrier between embryonic stem cells and trophoblast stem cells in mouse and human
(2023-04-19)
The placenta is a transient organ that exhibits various essential functions during pregnancy that allow for proper development of the embryo. Placenta and embryo originate from the first lineage separation in mammalian ...
Human iPSC-derived in vitro models of the peripheral nervous system for cellular pain and somatosensation research
(2022-01-07)
The term 'somatosensation' summarizes the sensation of touch, body position, temperature and pain experienced by animals or humans. Peripheral sensory neurons can be classified according to their primary sensation as ...
Funktion des Eisen-Schwefelflavoproteins DsrL im dissimilatorischen Schwefelstoffwechsel
(2024-05-21)
Das FeS-Cluster enthaltende Flavoprotein DsrL besitzt NAD(P)H-Oxidoreduktase-Aktivität und dient als Elektronendonor oder -akzeptor für die von DsrAB katalysierte Reaktion während der dissimilatorischen Sulfat/Sulfit-Reduktion ...
The yeast prion domain Sup35 NM models features of human neurodegenerative diseases in vivo
(2024-05-21)
In neurodegenerative diseases, such as prion diseases and Alzheimer’s disease, disease- associated proteins misfold and form amyloid deposits that progressively invade the CNS, leading to severe neurodegeneration. Accumulating ...
G protein-coupled receptors mobilize intracellular calcium via the Gs-βγ-PLCβ module
(2024-05-22)
(noch nicht zugänglich / not yet accessible)
Role of TLR2 in immune sensing of gut microbiota in RNA virus induced glomerulonephritis
(2024-05-22)
Chronically infected patients with human immune deficiency virus (HIV) are at high risk of developing autoimmune diseases. Despite successful anti-retroviral therapy, autoimmune diseases and renal diseases affect 10–15 % ...
Alzheimer’s and inflammation: exploring the interplay between immune cells in the peripheral immune system and the central nervous system through single-cell RNA-seq
(2024-05-23)
Alzheimer’s disease (AD) is a progressive neurodegenerative disease that is the most common cause of dementia and the sixth leading cause of death globally (Haque & Levey, 2019; World Health Organization, 2017). Increases ...