Faculties of University Bonn: Search
Now showing items 1291-1300 of 1330
Protein markers of inflammation and ageing in a European multi-centre dementia cohort
(2024-03-01)
Inflammation plays a key role in Alzheimerʼs disease (AD) progression. Microglia in the AD brain are exposed to pathological amyloid β (Aβ42) and tau peptide aggregates, resulting in the NLRP3 inflammasome activation ...
Organization principles of thalamocortical input onto deep-layer inhibitory neurons of the barrel cortex
(2024-02-28)
Thalamus functions as the main route by which incoming sensory information reaches the cerebral cortex. Thalamic nuclei will receive input from the sensory receptors in the periphery and relay it to different areas in the ...
Loss of protamine 1 and actin-like 7b – Investigating genes relevant for male fertility
(2024-02-13)
Sperm express a suite of genes specific to the testis. While they likely play essential roles in genes.
One of the key events during spermatogenesis is the replacement of histones by protamines. This leads to ...
One of the key events during spermatogenesis is the replacement of histones by protamines. This leads to ...
Comparison of human and porcine aortic valve endothelial and interstitial cells
(2024-02-13)
Calcific aortic valve disease (CAVD) is one of the most common heart valve pathologies and a major cause of morbidity and mortality in the elderly population. The disease is characterized by the gradual accumulation of ......
The mesoscale organization of Syntaxin 1A and SNAP25 at the plasma membrane
(2023-03-09)
The plasma membrane is a highly crowded place consisting of a plethora of proteins and lipids, which show a high degree of micropatterning. Most proteins are not homogeneously distributed but concentrated in clusters. ...
Elucidating the genetic basis and environmental regulation of root-microbe associations in maize
(2024-05-07)
Microorganisms play a critical role in promoting plant growth and performance, especially under environmental stresses. Utilization of microbiomes has been proposed as a strategy to improve food production and support ......
Mikroorganismen spielen eine entscheidende Rolle bei der Förderung des Pflanzenwachstums und der Pflanzenleistung, insbesondere unter biotischem und abiotischem Stress. Es wurde gezeigt, dass bestimmte wurzelassoziierte ......
Mikroorganismen spielen eine entscheidende Rolle bei der Förderung des Pflanzenwachstums und der Pflanzenleistung, insbesondere unter biotischem und abiotischem Stress. Es wurde gezeigt, dass bestimmte wurzelassoziierte ......
Evaluation of Striatin as a novel Microtubule Modulator
(2023-04-13)
The dynamics of the cell cycle and cell division are governed by tubulin polymers, i. e. microtubules (MTs). Defects of MT assembly or disassembly lead to pathogenic cellular conditions, negatively affecting cell viability, ......
GPR183 controls spatial organization and survival of hepatic conventional dendritic cells within hepatic portal regions via M-CSF and Gas6
(2023-04-19)
G protein-coupled receptor 183 (GPR183) recognizes 7α,25-dihydroxycholesterol (7α,25-OHC) and exerts chemotactic action upon recognition. Recent studies have shown that GPR183 is highly expressed in T, B and dendritic cells ...
Neuroanatomie und Funktionsmorphologie Peripherer Rezeptorneurone mit Direkten Projektionen in das Protocerebrum des Insektengehirns
(2023-04-20)
Zur Wahrnehmung unterschiedlicher thermischer Reize hat sich bei Insekten eine Reihe von Thermorezeptoren entwickelt. Der pyrophile („feuerliebend“) „Australische Feuerkäfer“ (Merimna atrata) besitzt paarige Infrarot-(IR)-Organe ......
Ectopic expression of transcription factors to overcome the lineage barrier between embryonic stem cells and trophoblast stem cells in mouse and human
(2023-04-19)
The placenta is a transient organ that exhibits various essential functions during pregnancy that allow for proper development of the embryo. Placenta and embryo originate from the first lineage separation in mammalian ...