Fakultäten der Universität Bonn: Suche
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Charakterisierung der Neddylierung von Cofilin1: Einfluss auf die neuronale Entwicklung
(2022-12-22)
Nachdem lange davon ausgegangen wurde, dass die posttranslationale Modifikation durch Nedd8 nur bestimmte Culline und den Zellzyklus reguliert, sind in den vergangenen Jahren weitere neddylierte Proteine gefunden worden, ...
Cellular mechanoresponse to extracellular matrix shear strain and stiffness studied in a cell culture model of breast gland development
(2023-05-12)
Mechanobiological regulation is a crucial element for tissue development and homeostasis. Dysregulation of the normal mechanobiological microenvironment of cells is linked to disease and negatively affects cancer patients' ...
Activation Mechanisms of RIG-I
(2020-11-02)
(noch nicht zugänglich / not yet accessible)
Establishing blood-based classifiers for decentralized and privacy-preserving disease prediction
(2024-04-08)
Big data is increasingly being generated across all sectors of medicine and high-dimensional omics data have been shown to be a powerful data space for AI applications that can assist in primary and differential diagnostics, ...
Novel lipoate-binding proteins and their role in sulfur oxidation
(2024-04-29)
The global sulfur cycle is a highly complex network of interconnected processes that involve the conversion of organic and inorganic sulfur compounds across multiple redox states. Driven by prokaryotes through the oxidation, ......
The Immune Memory Response and Metabolic Requirements of Human Gamma Delta T Cells
(2024-05-14)
γδ T cells are unconventional T cells that can mediate pro-inflammatory, cytotoxic, phagocytotic and professional antigen presenting properties. Sharing the features of both adaptive and innate immunity, γδ T cells also ...
Engagement of NKT cells during cross-priming enhances the CD8+ T cell response via GATA3 and IL-4/TNFα
(2022-04-21)
(noch nicht zugänglich / not yet accessible)
Modulation of filamin C interactions and function by mechanical stress-induced phosphorylations
(2024-06-24)
(noch nicht zugänglich / not yet accessible)
Identification of molecular mechanisms that may contribute to the antidepressant effect of St. John's wort extract Ze 117
(2024-06-25)
Chronic stress is one of the factors that contribute to the development and maintenance of depression. Previous studies have shown that the treatment of cultured cells with the natural stress hormone cortisol, but also ...
The role of CH25H in adipose tissue - a new potential target in anti-obesity therapy?
(2024-06-25)
Obesity associates with comorbidities as hypertension, cardiovascular disease, metabolic syndrome and type 2 diabetes mellitus and therefore depicts an emerging health issue. On a molecular level, obesity is accompanied ......