Fakultäten der Universität Bonn: Suche
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Consistently closing global and regional sea level budgets
(2022-11-17)
Nowadays, human-induced climate change is the major driver of global and regional sea level change threatening the well-being and livelihoods of hundreds of millions of people living close to the coast. Consequently, ...
Impact of aging and enriched environment on α-synuclein propagation
(2022-04-06)
Parkinson's disease (PD) is the second most common neurodegenerative disease. The prevalence of sporadic PD results from a complex interaction of demographic, genetic, and environmental factors. Age is one of the strongest ...
Human iPSC-derived in vitro models of the peripheral nervous system for cellular pain and somatosensation research
(2022-01-07)
The term 'somatosensation' summarizes the sensation of touch, body position, temperature and pain experienced by animals or humans. Peripheral sensory neurons can be classified according to their primary sensation as ...
Modifikationen der Reimplantationstechnik bei Aortenwurzelaneurysmata
(2022-12-15)
Veränderungen sowohl im Bereich der Aortenklappe als auch der Aortenwurzel, können zur Insuffizienz der Aortenklappe und strömungsphysikalischen Beeinträchtig des Flussverhaltens führen. Die Therapie der Aorteninsuffizienz ...
Engagement of NKT cells during cross-priming enhances the CD8+ T cell response via GATA3 and IL-4/TNFα
(2022-04-21)
(noch nicht zugänglich / not yet accessible)
Heavy metal contamination in urban agriculture and human health risk in Yaoundé, Cameroon
(2022-12-14)
Heavy metals are ubiquitous in the environment. The sources of heavy metals are both natural and anthropogenic activities. Urban growth, coupled with increasing demand for vegetables, has led to the utilization of lowlands ......
Schwermetalle sind allgegenwärtig in der Umwelt. Die Quelle für Schwermetalle sind sowohl natürlich als auch von Menschen verursachte Aktivitäten. Das Wachstum der Städte und die damit einhergehende steigende Nachfrage ......
Schwermetalle sind allgegenwärtig in der Umwelt. Die Quelle für Schwermetalle sind sowohl natürlich als auch von Menschen verursachte Aktivitäten. Das Wachstum der Städte und die damit einhergehende steigende Nachfrage ......
Role of IFN‑γ induced genes in cell autonomous defence against Legionellae
(2022-05-27)
L. pneumophila and L. longbeachae are ubiquitous environmental bacteria that can cause a severe pneumonia, known as Legionnaires’ Disease, when contaminated aerosols are inhaled by susceptible humans. During ......
Design, synthesis and optimization of receptor ligands: tools for studying purine-activated and related orphan G protein-coupled receptors
(2022-04-01)
Adenosine receptors
The A2A and A2B adenosine receptors (ARs) are promising drug targets in Alzheimer´s and Parkinson´s disease, inflammatory diseases, autoimmune diseases, ...
The A2A and A2B adenosine receptors (ARs) are promising drug targets in Alzheimer´s and Parkinson´s disease, inflammatory diseases, autoimmune diseases, ...
Effect of deoxyribonuclease-deficiency on myeloid cells under homeostatic and inflammatory conditions
(2022-12-27)
In healthy and diseased individuals, endogenous nucleic acids are present in various forms and need to be processed and cleared. Failed clearance of DNA is associated with an autoimmune disease termed systemic lupus ...
Charakterisierung der Neddylierung von Cofilin1: Einfluss auf die neuronale Entwicklung
(2022-12-22)
Nachdem lange davon ausgegangen wurde, dass die posttranslationale Modifikation durch Nedd8 nur bestimmte Culline und den Zellzyklus reguliert, sind in den vergangenen Jahren weitere neddylierte Proteine gefunden worden, ...