Faculties of University Bonn: Search
Now showing items 851-860 of 8591
Small-scale studies of the Milky Way disc and halo gas with absorption-line spectroscopy
(2012-12-13)
Progressive studies in the last decades have shown that the interstellar medium (ISM) is more complex and dynamic than previously thought. The presence of the small-scale structures, structures on scales below 1 pc, has ...
Neural crest development in a human embryonic stem cell-based model system
(2012-09-03)
The neural crest is a transient embryonic cell population with outstanding characteristics. After their delamination from the closing neural tube, neural crest cells migrate extensively throughout the body and differentiate ......
Bei der Neuralleiste handelt es sich um eine transiente, embryonale Zellpopulation mit außergewöhnlichen Eigenschaften. Nach Verlassen des sich schließenden Neuralrohres migrieren die Neuralleistenzellen durch den Körper ......
Bei der Neuralleiste handelt es sich um eine transiente, embryonale Zellpopulation mit außergewöhnlichen Eigenschaften. Nach Verlassen des sich schließenden Neuralrohres migrieren die Neuralleistenzellen durch den Körper ......
Selberg and Ruelle zeta functions and the relative analytic torsion on complete odd-dimensional hyperbolic manifolds of finite volume
(2012-08-27)
Let X be a complete hyperbolic manifold of finite volume and of odd dimension d. Firstly, we study Selberg zeta functions on X, prove that these functions have a meromorphic continuation to the entire complex plane and ...
Identification of genetic factors involved in the regulation of stress
(2012-08-29)
In this QTL mapping study, several genetic regions were linked to anxiety- and depression-related behavior in the mouse. Furthermore, some previously identified QTL linked to these behavioral traits were verified in the ...
Design Rules in VLSI Routing
(2012-08-17)
One of the last major steps in the design of highly integrated circuits (VLSI design) is routing. The task of routing is to compute disjoint sets of wires connecting different parts of a chip in order to realize the desired ...
Grained integers and applications to cryptography
(2012-05-24)
To meet the requirements of the modern communication society, cryptographic techniques are of central importance. In modern cryptography, we try to build cryptographic primitives, whose security can be reduced to solving ...
Novel lantibiotics from microbial genomes
(2012-07-19)
The discovery of antibiotics was one of the most important milestones in medicine and in the fight against infectious disease. Today, more than 80% of anti-infective drugs are natural or semi-synthetic compounds. Rapidly ...
Computational Analysis of Structure-Activity Relationships: From Prediction to Visualization Methods
(2012-07-18)
Understanding how structural modifications affect the biological activity of small molecules is one of the central themes in medicinal chemistry. By no means is structure-activity relationship (SAR) analysis a priori ...
Revealing the Mechanism of Thiopeptide Antibiotics at Atomistic Resolution: Implications for Rational Drug Design
(2012-07-18)
For decades drug design has primarily focused on small molecules that bind to well-formed tight binding pockets, such as the catalytic centers of enzymes. Recently, there is increasing interest to design compounds that ...
A Mathematical Model of the Potassium Homeostasis in Saccharomyces cerevisiae
(2012-07-20)
Without potassium, all living cells will die; it has to be present in sufficient amounts for the proper function of most cell types. Disturbances in potassium levels in animal cells result in potentially fatal conditions ...