Faculties of University Bonn: Search
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Molecular Mechanisms of NLRP3 Inflammasome Activation: Involvement of the Leucine-Rich Repeat Domain and Charcot-Leyden Crystals
(2021-07-29)
Chronic inflammation is a major driver of several non-communicable diseases. The cytosolic pattern recognition receptor NLRP3 is involved in the development of many of these diseases, as its activation in innate immune ...
Investigation of Heat Shock Protein 70 and Toll-like Receptor 4 functions during inflammation reaction by mechanical compression in human periodontal ligament cells
(2021-06-24)
Biomechanical forces exerted during treatment with orthodontic appliances cause tensile and compressive strain within the periodontal ligament (PDL) of affected teeth followed by ischemia on the compression side. Further, ...