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Extracellular vesicles derived from Hepatitis-D Virus infected cells induce a proinflammatory cytokine response in human peripheral blood mononuclear cells and macrophages
(2020-02-14)
Hepatitis D Virus (HDV) is a satellite virus requiring a Hepatitis B Virus (HBV) envelope
proteins for productive infection. Hepatitis D is the most severe form of viral hepatitis
and is a global health threat affecting ...
Intervertebral Disc and Adipokine Leptin—Loves Me, Loves Me Not
(2020-12-31)
Leptin—the most famous adipose tissue-secreted hormone—in the human body is mostly observed in a negative connotation, as the hormone level increases with the accumulation of body fat. Nowadays, fatness is becoming another ...
Optimizing the Target-based Calibration Procedure of Terrestrial Laser Scanners: Optimierung des zielzeichenbasierten Kalibrierprozesses terrestrischer Laserscanner
(2020)
Terrestrial laser scanner (TLS) measurements suffer from systematic errors due to internal misalignments. The magnitude of the resulting errors in the point cloud exceeds the magnitude of random errors in many applications. ...
Assessing the quality of life of patients with metastatic castration-resistant prostate cancer with bone metastases receiving [223Ra]RaCl2 therapy
(2020-08-19)
[223Ra]RaCl2 dichloride treatment in patients with metastatic castration-resistant prostate cancer (mCRPC) is associated with improved overall survival (OS) and a delay in the time to the first ...
Current flood risk management practices in Ghana: Gaps and opportunities for improving resilience
(2020-09-02)
This article evaluates the current gaps and describes opportunities for improving flood risk management (FRM) in Ghana, West Africa. A mixed-method participatory approach comprising questionnaires, workshops, interviews ...
Regenerated Hoof Keratin from 1-Ethyl-3-Methylimidazolium Acetate and Insights into Disulfide-Ionic Liquid Interactions from MD Simulation
(2020-06-08)
Regeneration of the hoof keratin from ionic liquids was never successful in the past because the ionic liquids were not strong enough. However, this biomaterial starts to play a central role for the preparation of biofilms ...
Acid-Catalyzed Rearrangements of 3-Aryloxirane-2-Carboxamides: Novel DFT Mechanistic Insights
(2020-07-01)
Efficient synthesis of 3-arylquinolin-2(1H)-ones and N-(2-carboxyaryl)-oxalamides from protic acid-catalyzed rearrangements of 3-aryloxirane-2-carboxamides was achieved recently but not well understood. In contrast to the ...
Population size estimates based on the frequency of genetically assigned parent–offspring pairs within a subsample
(2020-07-24)
Estimating population density as precise as possible is a key premise for managing wild animal species. This can be a challenging task if the species in question is elusive or, due to high quantities, hard to count. We ...
Activity coefficients of binary methanol alcohol mixtures from cluster weighting
(2020-07-23)
The hydrogen bond network of different small alcohols is investigated via cluster analysis. Methanol/alcohol mixtures are studied with increasing chain length and branching of the molecule. Those changes can play an important ...
UDP-glucuronosyltransferase polymorphisms affect diethylnitrosamine-induced carcinogenesis in humanized transgenic mice
(2020-08-28)
UDP-glucuronosyltransferase (UGT) 1A enzymes detoxify a broad array of exogenous compounds including environmental toxins and carcinogens. Case-control studies identified genetic variations in UGT1A genes leading to reduced ...