Fakultäten der Universität Bonn: Suche
Anzeige der Dokumente 1641-1650 von 2302
Investigation of Phthalazine, Quinazoline and Pyrimidine Derivatives as ABCG2 Inhibitors
(2018-08-28)
Globally, cancer is the second leading cause of death. Chemotherapy is commonly used in the treatment of cancer. However, in clinic, a wide variety of cancers display resistance to chemotherapy leading to the failure of ...
The role of the endocannabinoid receptor CB2 in a mouse model of Alzheimer's disease
(2018-09-26)
Over the past years, an important role of the cannabinoid receptor 2 (CB2) has been implicated in several neurological and immunological conditions, such as experimental autoimmune encephalitis, stroke, memory, neuropathic ......
Therapeutic effects of wetlands on mental well-being: The concept of therapeutic landscapes applied to an ecosystem in Uganda
(2018-07-03)
The therapeutic effects of wetlands help to keep people mentally healthy. Especially in developing countries, health care prioritizes the treatment and prevention of physical illness before mental illness due to the high ...
The mind's ratio: How the balance between ω-6 and ω-3 fatty acids affects the risk of late-life dementia
(2022-02-03)
Dementia health care costs are rapidly rising due to the increasing number of people with dementia worldwide that is expected to increase to 66 million by 2030 and 115 million by 2050 (Prince et al., 2013). Intensive ......
Locus coeruleus modulates locomotor activity via the medial septum and the diagonal band of Broca
(2020-10-02)
The locus coeruleus (LC) is positioned in the brainstem and one of the main sources of norepinephrine in the brain. With its projections throughout the whole brain, the LC plays an important role in regulating the general ...
Mütterliche Adipositas während Schwangerschaft und Säugezeit als Risiko für die Entwicklung kognitiver Defizite beim Nachwuchs
(2018-05-22)
Morbus Alzheimer ist die häufigste neurodegenerative Erkrankung weltweit mit stetig steigender Inzidenz. Nur ein kleiner Anteil der Fälle ist rein genetisch bedingt, die meisten Krankheitsfälle sind durch multiple ...
Untersuchungen zum Metabolismus und Nachweisfenster von γ-Hydroxybuttersäure in biologischem Material
(2018-03-19)
In dieser Arbeit wurden interdisziplinäre Untersuchungen durchgeführt, um die Nachweisbarkeitsdauer nach einer Gamma-Hydroxybuttersäure-(GHB)-Gabe in biologischen Matrices zu verlängern. Es sollten biologische Marker ...
Fast detection of protein-protein interactions with an automated FRET-based system on the flow cytometer
(2018-03-12)
Although protein-protein interactions play a major role in almost all biological functions, those interactions cannot easily be analysed, especially not on single cell level and with regard to dynamic changes in protein ...
Lipide als Transport- und Signalmoleküle: Untersuchungen in Makrophagen und Neuronen
(2018-04-17)
Lipide haben einen großen Anwendungsbereich und speziell in der Biochemie des lebenden Organismus wichtige Funktionen. Neben ihrer hauptsächlichen Funktion als Energiespeicher und Strukturkomponenten der Zellmembranen ...
The importance of endogenous opioids in feeding behavior
(2018-03-14)
Endogenous opioids are involved in a broadly distributed neural network regulating eating behavior. Opioid transmission has long been implicated in controlling hedonic and homeostatic feeding as well as regulating body ......