The Faculty of Medicine: Browsing Medizinische Fakultät by Author "Isbrandt, Dirk"
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A basal forebrain to midbrain circuit drives exploratory locomotion
Mocellin, Petra (2023-10-26)Locomotion is a fundamental behavior that comprises different specialized neuronal networks. In the basal forebrain, the glutamatergic neurons of the medial septum and diagonal band of Broca (MSDB<sub>glu</sub>) can initiate ... -
Altered Dendritic Excitability and Cell Maturation of CA3 Pyramidal Neurons During Development in the SCN2AA263V Genetic Epilepsy Model
Barboni, Michela (2024-01-16)Gain of fUnction variants of the Nav1.2 sodium channel are strongly associated with various developmental disorders, as a common feature. Although previous studies in heterologous expression systems have identified the ... -
Participation of Ste20-like kinase-deficient neurons in the abnormal circuitry of focal epileptogenic lesions
Royero Rodriguez, Pedro Xavier (2022-01-03)Focal epileptogenic lesions displaying morphologically altered neurons are frequently associated with devastating and therapy-refractory epilepsies. However, it is still unsolved how dysplastic neurons contribute to the ...