Medizinische Fakultät
Teilbereiche in diesem Bereich
Sammlungen in diesem Bereich
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E-Dissertationen (2078)
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Publikationen (7)
Neueste Zugänge
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Molecular pathomechanisms of immune-mediated epileptogenesis
(2025-12-03)This thesis explores the immune-mediated and molecular mechanisms underlying AE and epileptogenesis, with a particular emphasis on T cell-dependent neuroinflammation and the transcriptional dynamics across different stages ... -
Evaluation der Beatmungstherapie mithilfe der elektrischen Impedanztomografie bei Kindern mit schwerem Lungenversagen: Eine prospektive Feasibility-Studie
(2025-12-02)Die vorliegende Arbeit untersucht die Möglichkeiten der EIT zur Evaluation der invasiven Beatmungstherapie bei Kindern mit schwerem Lungenversagen. Dabei zeigt sie, dass EIT Messungen mit absteigenden PEEP Titrationen bei ... -
Functional genomics approaches to study healthy and unhealthy aging in the Rhineland Study
(2025-12-02)Aging is a complex and heterogeneous process, characterized by a decline in physiological functions and an increased risk of various diseases, including cardiovascular, neurodegenerative, and metabolic disorders. Although ... -
Anwendung der repetitiven transkraniellen Magnetstimulation mit akzeleriertem Protokoll bei Parkinson-Krankheit
(2025-11-21)<strong>Hintergrund</strong> <br/> Die repetitive transkranielle Magnetstimulation (rTMS) ist eine nicht-pharmakologische und nicht-invasive Hirnstimulationstechnik, die sich bei der Parkinson-Krankheit (PK) als wirksam ... -
Entwicklung der Wirkstoffzusammensetzung von Händedesinfektionsmitteln in Deutschland von 2004 bis 2022 unter besonderer Berücksichtigung von Ethanol
(2025-11-21)<strong>Zielsetzung:</strong> Analysiert wurde die Anzahl der in Händedesinfektionsmitteln (HD) eingesetzten Wirkstoffe in Deutschland anhand der Desinfektionsmittel-Listen des Verbunds für Angewandte Hygiene (VAH) der ... -
Numerische Simulation des nichtlinearen Versagensverhaltens bei der Prüfung der Scherhaftfestigkeit in der Zahnmedizin
(2025-11-20)Ziel dieser Studie war die Entwicklung eines numerischen Modells zur Simulation von Scherhaftfestigkeitstests unter Berücksichtigung unterschiedlicher Probengrößen (Makro/Mikro) und Belastungstechniken (Klinge/Drahtschlaufe). ... -
Platelet-derived transcription factors as modulators of NFκB-dependent inflammatory responses in human monocytes
(2025-11-20)Platelets have immunomodulatory roles beyond their classical function in hemostasis, for example regulating monocyte-driven inflammation. Classical CD14<sup>+</sup> monocytes dominate in human blood and mediate immune ... -
Implementing a meningioma organoid platform for testing new treatment approaches
(2025-11-17)Meningioma represents the most common type of brain tumor, accounting for approximately 38.3% of all cases. Despite its prevalence, severe symptoms and potential lethality in high-grade forms, current therapeutic strategies ... -
Short physical performance battery: Pilot study of a human motion capture app (MobiSPPB)
(2025-07-02)<strong>Background:</strong> A standardized fall risk assessment can guide targeted interventions. The widely used short physical performance battery (SPPB) for mobility assessment covers balance, gait speed, and lower ... -
Case Report: Practical approach to unmask unspecific adverse effects under lipid-lowering medication
(2025-05-27)The nocebo effect, driven by negative expectations rather than pharmacological mechanisms, contributes significantly to medication non-adherence, particularly in lipid-lowering therapy. Up to 50% of reported statin-related ... -
Primary cilia signalling at a glance
(2025-10-29)The primary cilium is a solitary, microtubule-based organelle present on most vertebrate cells, where it functions as a central hub for sensing and transducing extracellular signals. This Cell Science at a Glance article ... -
Phytochemical combinations of lichen Evernia prunastri (L.) Ach. reduce drug resistance to temozolomide but not to paclitaxelin vitro
(2025-09-15)<strong>Introduction:</strong> Temozolomide (TMZ) and Paclitaxel (PXT), crucial anti-cancer drugs for glioblastoma (GBM) and primary breast cancer (BC), respectively, face drug resistance. Therefore, we investigated the ... -
Retrospektive Analyse postoperativer Komplikationen nach Septumplastik: Korrelation der Prävalenz und des perioperativen Einsatzes einer Nasentamponade
(2025-11-12)<strong>Hintergrund:</strong> Die Septumplastik stellt ein gängiges chirurgisches Verfahren zur Behandlung der Nasenatmungsbehinderung auf dem Boden einer Septumdeviation dar. Der Einsatz einer Nasentamponade ist eine ... -
Functional and Molecular Characterization of Tolerized Langerhans Cells in Atopic Dermatitis: Mechanistic Insights into the TLR2-NF-κB Signaling Pathway
(2025-11-07)Atopic dermatitis (AD) represents the most common chronic, inflammatory, and recurrent disease intricately influenced by genetic and immune factors, with environmental interactions playing a pivotal role. Epidermal Langerhans ... -
Potential of Aframomum melegueta and Xylopia aethiopica Against Taenia spp.: Plant-Based Remedies as Novel Anthelmintics
(2025-05-19)<strong>Background/Objectives: </strong>Taeniasis, a zoonotic infection, is a common foodborne disease. Niclosamide and praziquantel have proven to be effective in treating it, but the use of the same drugs can lead to ... -
Evaluating the accuracy of generative artificial intelligence models in dental age estimation based on the Demirjian's method
(2025-07-29)<strong>Introduction:</strong> Dental age estimation plays a key role in forensic identification, clinical diagnosis, treatment planning, and prognosis in fields such as pediatric dentistry and orthodontics. Large language ... -
Sialylation as a checkpoint for inflammatory and complement-related retinal diseases
(2025-06-27)Sialylation is a modification process involving the addition of sialic acid residues to the termini of glycoproteins and glycolipids in mammalian cells. Sialylation serves as a crucial checkpoint inhibitor of the complement ... -
Longitudinale Charakterisierung von strukturellen Biomarkern bei intermediärer altersabhängiger Makuladegeneration (AMD)
(2025-11-06)In dieser longitudinalen Studie wurde der Einfluss struktureller Hochrisiko-Biomarker auf die Krankheitsprogression bei nicht-exsudativer altersabhängiger Makuladegeneration (AMD) mittels räumlich aufgelöster mesopischer ... -
Deep brain imaging of neuronal activity in sensory thalamus during innate and learned avoidance behavior
(2025-11-06)Avoidance behaviors are critical for survival, enabling organisms to respond effectively to potential threats in their environment. While much is known about how cortical and limbic brain areas contribute to avoidance ...
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