The Faculty of Medicine
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E-Dissertationen (2070)
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Publikationen (7)
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Short physical performance battery: Pilot study of a human motion capture app (MobiSPPB)
(2025-07-02)<strong>Background:</strong> A standardized fall risk assessment can guide targeted interventions. The widely used short physical performance battery (SPPB) for mobility assessment covers balance, gait speed, and lower ... -
Case Report: Practical approach to unmask unspecific adverse effects under lipid-lowering medication
(2025-05-27)The nocebo effect, driven by negative expectations rather than pharmacological mechanisms, contributes significantly to medication non-adherence, particularly in lipid-lowering therapy. Up to 50% of reported statin-related ... -
Primary cilia signalling at a glance
(2025-10-29)The primary cilium is a solitary, microtubule-based organelle present on most vertebrate cells, where it functions as a central hub for sensing and transducing extracellular signals. This Cell Science at a Glance article ... -
Retrospektive Analyse postoperativer Komplikationen nach Septumplastik: Korrelation der Prävalenz und des perioperativen Einsatzes einer Nasentamponade
(2025-11-12)<strong>Hintergrund:</strong> Die Septumplastik stellt ein gängiges chirurgisches Verfahren zur Behandlung der Nasenatmungsbehinderung auf dem Boden einer Septumdeviation dar. Der Einsatz einer Nasentamponade ist eine ... -
Functional and Molecular Characterization of Tolerized Langerhans Cells in Atopic Dermatitis: Mechanistic Insights into the TLR2-NF-κB Signaling Pathway
(2025-11-07)Atopic dermatitis (AD) represents the most common chronic, inflammatory, and recurrent disease intricately influenced by genetic and immune factors, with environmental interactions playing a pivotal role. Epidermal Langerhans ... -
Potential of Aframomum melegueta and Xylopia aethiopica Against Taenia spp.: Plant-Based Remedies as Novel Anthelmintics
(2025-05-19)<strong>Background/Objectives: </strong>Taeniasis, a zoonotic infection, is a common foodborne disease. Niclosamide and praziquantel have proven to be effective in treating it, but the use of the same drugs can lead to ... -
Evaluating the accuracy of generative artificial intelligence models in dental age estimation based on the Demirjian's method
(2025-07-29)<strong>Introduction:</strong> Dental age estimation plays a key role in forensic identification, clinical diagnosis, treatment planning, and prognosis in fields such as pediatric dentistry and orthodontics. Large language ... -
Sialylation as a checkpoint for inflammatory and complement-related retinal diseases
(2025-06-27)Sialylation is a modification process involving the addition of sialic acid residues to the termini of glycoproteins and glycolipids in mammalian cells. Sialylation serves as a crucial checkpoint inhibitor of the complement ... -
Longitudinale Charakterisierung von strukturellen Biomarkern bei intermediärer altersabhängiger Makuladegeneration (AMD)
(2025-11-06)In dieser longitudinalen Studie wurde der Einfluss struktureller Hochrisiko-Biomarker auf die Krankheitsprogression bei nicht-exsudativer altersabhängiger Makuladegeneration (AMD) mittels räumlich aufgelöster mesopischer ... -
Deep brain imaging of neuronal activity in sensory thalamus during innate and learned avoidance behavior
(2025-11-06)Avoidance behaviors are critical for survival, enabling organisms to respond effectively to potential threats in their environment. While much is known about how cortical and limbic brain areas contribute to avoidance ... -
Gingivaresektion mit Diodenlasern der Wellenlänge 445 nm und 970 nm: Auswertung der Pilotphase einer klinischen Vergleichsstudie
(2025-11-06)Im Rahmen einer Pilotstudie wurde ein 445 nm-Laser mit einem 970 nm-Laser als Testsystem für Gingivektomie-Maßnahmen verglichen. Insgesamt wurden 20 Zähne von acht Patienten behandelt. Der Untersuchungszeitraum erstreckte ... -
AI-Enhanced 3D Models in Global Virtual Reality Case Conferences for Surgical Care in a Low-Income Country: Exploratory Study
(2025-08-18)<strong>Background: </strong>Approximately 5 billion people worldwide lack adequate access to surgical care, primarily in the Global South. Especially in crisis regions and war zones, telemedical applications may enhance ... -
Drinking Water and Sanitation Safety Planning for Medical Facilities: An Innovative PoU Approach for a Water System Description Using Ecomaps
(2025-06-26)Drinking Water Safety Plans (DWSP) in buildings serve to identify health hazards associated with the drinking water system. Sanitation Safety Plans (SSP) fulfill the same purpose for the sewage system. Water Safety Plans ... -
Quantitative and qualitative tremor evaluation after MR-guided focused ultrasound thalamotomy
(2025-05-02)<strong>Introduction:</strong> Tremor syndromes are common neurological disorders, usually distinguished by clinical examination. Ordinal rating scales are widely used to rate tremor severity but are limited by subjective ... -
Neuropilin 2 in Osteoblasten
(2025-11-05)Neuropilin-2 (Nrp2) wird zunehmend als potenzielles therapeutisches Ziel bei Knochenmetastasen des kastrationsresistenten Prostatakarzinoms (CRPC) diskutiert. Es spielt eine Rolle in der Regulation der Osteogenese, doch ... -
In vitro Charakterisierung der antiproliferativen Wirksamkeit von nicht-invasivem physikalischem Plasma (NIPP: Non invasive physical plasma) in den drei gynäkologischen Malignitäten Leiomyosarkom (SK-UT-1), Mammakarzinom (MCF-7 und MDA-MB- 231) und Endometriumkarzinom (MFE-296)
(2025-11-03)Die bösartige Neoplasie der Brustdrüse ist die häufigste Todesursache bei Frauen zwischen dem 35. und 55. LJ. Das EC betrifft am häufigsten postmenopausale Frauen, um das Alter von 68 Jahren. Mit einer Inzidenz in Deutschland ... -
Kutane Nebenwirkungen und Supportivtherapie im Kontext der adjuvanten Bestrahlung des Mammakarzinoms
(2025-10-31)<strong>Hintergrund:</strong> Kutane Nebenwirkungen stellen die häufigste akute Nebenwirkung der adjuvanten Strahlentherapie beim Mammakarzinom dar. Akute Radiodermatitis betrifft bis zu 85 % der Patientinnen und kann ... -
A new generation of patient-reported outcome measures with large language models
(2025-03-24)<strong>Background</strong> Patient-reported outcome measures (PROMs) are cornerstones of patient-centered clinical medicine and reflect patients' abilities, difficulties, perceptions and behaviors. The highly structured ... -
Fibroblast growth factor receptor 2 (FGFR2) genetic polymorphisms contribute to fused roots in human molars
(2025-04-10)Fibroblast growth factors (FGFRs) signaling are required for human tooth development. Its dysregulation affects tooth formation and patients with <em>FGFR2</em> mutations often present dental anomalies in the spectrum of ...
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