Medizinische Fakultät
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E-Dissertationen (2101)
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Publikationen (7)
Neueste Zugänge
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Diagnostische und prognostische Aussagekraft von perioperativem NT-proBNP in Serum und Urin bei Kindern mit angeborenen Herzfehlern
(2026-01-14)NT-proBNP ist ein wichtiger Marker für Kinder mit angeborenen Herzfehlern. Gerade in diesem Kollektiv könnte sich ein Vorteil aus der Bestimmung des NT-proBNP aus dem Urin ergeben, da häufige Blutentnahmen bei dem geringem ... -
Strukturelle Veränderungen des Nucleus dentatus bei Mutationsträger*innen mit spinozerebellärer Ataxie Typ 3 / Machado-Joseph-Krankheit
(2026-01-13)Die spinozerebelläre Ataxie Typ 3 (SCA3) ist eine autosomal-dominant vererbte CAG-Triplett-Expansions-Erkrankung. In der manifesten (ataktischen) Phase der SCA3 ist diese klinisch von einer progredienten Ataxie gekennzeichnet. ... -
Zusammenhang zwischen der äußeren Netzhautreflektivität und der Netzhautfunktion bei altersabhängiger Makuladegeneration
(2026-01-13)Hintergrund: Bei der altersabhängigen Makuladegeneration (AMD) fehlen für frühe Krankheitsstadien sensitive, funktionell relevante Bildgebungsmarker, die als klinische Endpunkte in Interventionsstudien geeignet sind. Die ... -
Shortcoming of the Mouse Model of Postoperative Ileus: Small Intestinal Lengths Have Similar Variations in In- and Outbred Mice and Cannot Be Predicted by Allometric Parameters
(2025-11-30)<strong>Background/Objectives:</strong> The mouse model of postoperative ileus separates the gastrointestinal tract into 15 sections, 10 of which are in the small intestine, to measure intestinal transit time. Usually, ... -
Nutzen der MRT-basierten Fettquantifizierung zur nicht-invasiven Abschätzung des Differenzierungsgrades hepatozellulärer Karzinome
(2026-01-12)<strong>Zielsetzung</strong> <br/> Die bildbasierte Detektion von intraläsionalem Fett in fokalen Leberläsionen ist in diagnostischen Leitlinien als charakteristisches Merkmal für das hepatozelluläre Karzinom (HCC) etabliert ... -
Langzeitwirkungen von Cannabis-Abhängigkeit in Hinblick auf funktionale Veränderungen der Emotionsregulation
(2026-01-09)Cannabis ist die am häufigsten konsumierte illegale Substanz weltweit wobei ca. 10% der regelmäßig Konsumierenden eine Abhängigkeit entwicklen. Akute Effekte von Cannabis sind relativ breit untersucht, es fehlt an ... -
Noradrenergic Circuit Adaptations Underlying Predatory Aggression
(2026-01-09)Behaviors are adaptive traits shaped by natural selection. Nevertheless, the genetic, molecular, and neural modifications that underlie behavioral innovations remain poorly understood. Here, I identify specialized adaptations ... -
Evaluation und Analyse der Einflussfaktoren bei der Facharztwahl "Gynäkologie und Geburtshilfe" während verschiedenen Zeitpunkten im Medizinstudium: Eine Querschnittserhebung unter Studierenden
(2026-01-08)Es gibt einen weltweiten Mangel an Geburtshelfer*innen und Gynäkolog*innen (OB/GYN), was Anlass zur Sorge über die künftige Patientinnenversorgung und personelle Nachhaltigkeit gibt. Deutschland steht vor einem besonders ... -
Dopamine dynamics in the basolateral amygdala during associative learning and exploration
(2025-12-30)Dopamine release in the basolateral amygdala (BLA) is thought to contribute to salience attribution and associative learning; yet its role during self-paced behaviours has remained unexplored. Using fibre photometry combined ... -
Complete genome sequence of Pediococcus pentosaceus 13.7 2A-1 isolated from a Holstein Friesian dairy cattle
(2025-10-02)<em>Pediococcus pentosaceus</em> was isolated from a Holstein Friesian dairy cattle from a conventionally operated farm. The complete genome of strain <em>P. pentosaceus</em> 13.7 2A-1 comprises 1.84 Mbp and 1,746 ... -
Post-Surgical Outcomes of Kidney-Sparing Surgery vs. Radical Nephroureterectomy for Upper-Tract Urothelial Cancer in a Propensity-Weighted Cohort
(2025-08-25)Objectives: In localized upper-tract urothelial carcinoma (UTUC), radical nephroureterectomy (RNU) represents the surgical gold standard, but kidney-sparing surgery (KSS) offers an alternative. The surgical perspective, ... -
Potent optogenetic regulation of gene expression in mammalian cells for bioproduction and basic research
(2025-06-30)Precise temporal and spatial control of gene expression greatly benefits the study of specific cellular circuits and activities. Compared to chemical inducers, light-dependent control of gene expression by optogenetics ... -
Evaluating Sorafenib (SORA-2) as Second-Line Treatment for Unresectable Hepatocellular Carcinoma: A European Retrospective Multicenter Study
(2025-03-13)Background/Objectives: Systemic treatment for unresectable hepatocellular carcinoma (HCC) has rapidly advanced, with immune checkpoint inhibitors now the preferred first-line option. However, with multiple agents available ... -
In Vivo Cone Photoreceptor Topography of the Human Foveola
(2025-08-06)<strong>PURPOSE.</strong> To study in vivo cone topography of the normal human foveola. <br/> <strong>METHODS.</strong> The fovea in both eyes of 30 healthy participants was imaged with adaptive optics scanning light ... -
Mesiodistal width correlation between primary and successor mandibular teeth: implication for early orthodontic diagnosis
(2025-09-24)<strong>Background:</strong> Most studies on permanent tooth width prediction focus on the predictive value of permanent teeth, however only a few studies examine the predictive value of primary teeth. The aim of this study ... -
Strong Association of Perceived Chronic Stress with Leadership Quality, Work–Privacy Conflict and Quantitative Work Demands: Results of the IMPROVEjob Study
(2025-05-03)The health of primary care professionals is crucial for the health of populations. A lower number of general practitioners per 1000 patients correlates with higher patient mortality. Challenging work demands, work–privacy ... -
Missing images: autobiographical memory in Aphantasia and blindness
(2025-09-11)Mental visual imagery, especially the ability to construct naturalistic scenes seems central to vivid episodic autobiographical memory (AM). This mini review will first highlight the neural anatomy of different aspects of ... -
Microbiological Profiles of Patients with Acute Periprosthetic Joint Infection Undergoing Debridement, Antibiotics, Irrigation and Implant Retention (DAIR)
(2025-08-30)<strong>Background:</strong> Periprosthetic joint infection (PJI) is one of the most serious complications following total joint arthroplasty. The debridement, antibiotics, irrigation, and implant retention (DAIR) procedure ... -
Passive Blood-Flow-Restriction Exercise's Impact on Muscle Atrophy Post-Total Knee Replacement: A Randomized Trial
(2025-07-23)<strong>Background/Objectives:</strong> Total knee arthroplasty (TKA) is commonly associated with postoperative muscle atrophy and weakness, while traditional rehabilitation is often limited by pain and patient compliance. ... -
FVIII Trafficking Dynamics Across Subcellular Organelles Using CRISPR/Cas9 Specific Gene Knockouts
(2025-07-01)Factor VIII (FVIII) interacts with Endoplasmic Reticulum (ER) chaperones Calnexin (CANX) and Calreticulin (CALR) and with ER-Golgi Intermediate Compartment (ERGIC) transporters, Lectin, mannose-binding 1 (LMAN1) and Multiple ...
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