The Faculty of Medicine: Browsing Medizinische Fakultät by Classification (DDC) "ddc:540"
Now showing items 1-8 of 8
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Control of pulmonary immunity by physical exercise
Michla, Marcel (2024-03-06)Sedentary lifestyles combined with high caloric nutrition are widely known to severely contribute to the rise of metabolic diseases like diabetes, atherosclerosis, or obesity in recent years. While endurance training has ... -
The DEAH helicase DHX36 and its role in G-quadruplex-dependent processes
Schult, Philipp; Paeschke, Katrin (2020-10-12)DHX36 is a member of the DExD/H box helicasefamily, which comprises a large number of proteinsinvolved in various cellular functions. Recently, thefunction of DHX36 in the regulation of G-quadruplexes(G4s) was ... -
Inflammation-dependent differentiation of two distinct regulatory T cell populations in the visceral adipose tissue shapes systemic metabolism
Valle Torres, Stalin Santiago (2023-12-07)Visceral adipose tissue (VAT) is an endocrine organ critical for energy storage and metabolic homeostasis. It harbours a plethora of immune cells, which play an important role in maintaining tissue homeostasis. A large ... -
Investigating the ability of RIG-I agonists to provide protection in mouse and ferret models of respiratory virus infection
Schwab, Lara Sonja Ute (2022-05-17)Respiratory infections caused by influenza A virus (IAV) or respiratory syncytial virus (RSV) lead to substantial morbidity and mortality. Treatment options are limited and there is urgent need for the development of ... -
Lipid droplet formation drives pathogenic ILC2 responses in airway inflammation
Kharabi Masouleh, Schekufe (2020-06-08)The Western world is affected by a dramatic increase of chronic inflammatory diseases like asthma, Crohn’s disease and psoriasis. Innate lymphoid cells (ILC) play an important role in the control and maintenance of barrier ... -
Nanoparticle delivery of molecular agents to tackle HIV latency
Ali, Abdalla Abbas Jafer (2022-09-16)Antiretroviral therapy (ART) effectively suppresses HIV replication in people living with HIV (PLWH), but treatment is lifelong. The persistence of long-lived, latently infected resting CD4+T cells is a significant ... -
Nucleic acid sensing in CD4 T cells during HIV-1 and other viral infections
Holz, Marvin (2021-10-15)Viruses are small intracellular parasites and use the host cell’s biosynthesis machinery to replicate and spread. Therefore, viral particles incorporate structures that are similar to the ones that naturally occur within ... -
Ribosome profiling of selenoproteins in vivo reveals consequences of pathogenic Secisbp2 missense mutations: The establishment of translating ribosome affinity purification
Zhao, Wenchao (2020-11-04)Recoding of in-frame UGA/Seccodon in selenoproteins requires a complex translational machinery. The core of this event is the interaction between selenocysteine insertion sequence (SECIS element) in the 3’UTR of ...