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Interplay of IKKs and IKK-related kinases in antiviral nucleic acid receptor signaling in human monocytes
(2022-06-21)
Monocytes and monocyte-derived cells are among the first line of host defense against
invading pathogens. They are equipped with pattern recognition receptors (PRRs) that
detect conserved components of microbes and in ...
Immune activation by DNA sensors in ANCA associated vasculitis
(2024-03-04)
Anti-neutrophilic cytoplasmatic antibody (ANCA) associated vasculitis (AAV) is a group of rare inflammatory autoimmune diseases primarily affecting the small vessels of kidney and lung. Current treatment options mainly ...