Mathematisch-Naturwissenschaftliche Fakultät: Suche
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Molekulare Mechanismen der Kreuzpräsentation
(2013-06-14)
Ein Schlüsselwerkzeug zur Aktivierung und Tolerisierung zytotoxischer CD8+ T-Zellen ist die Kreuzpräsentation. Die Aufklärung zellulärer und molekularer Mechanismen der Kreuzpräsentation und ihrer Folgen ist ......
Spin and Flavour dependent Interactions within a Quark Model for Baryons
(2013-06-14)
Within the framework of a relativistic covariant quark model the effects of two novel quark interactions on the light-flavoured baryon mass spectra as well as on a multitude of observables, such as electroweak form factors, ...
Die Biosynthese und der Transport von N-Acetylaspartylglutamat und N-Acetylaspartylglutamylglutamat
(2013-07-10)
N-Acetylaspartylglutamat (NAAG) ist eines der höchst konzentrierten Neuropeptide im Nervensystem von Säugetieren. Neben der postulierten Rolle als Agonist für den Typ II metabotropen Glutamatrezeptor 3. Zusätzlich dient ...
The Farrell-Jones conjecture for some general linear groups
(2013-07-10)
In this thesis I prove the K- and L-theoretic Farrell-Jones conjecture with coefficients in any additive category for the general linear groups of F(x) for a finite field F. I also show that the general linear groups over ...
Determination of the Hubble constant from the strong lensing system B0218+357
(2013-07-08)
Gravitational lensing and particularly strong lensing provide variety of subjects to study such as galaxy evolution, substructure detection in galaxies or cluster of galaxies. Also strong lensing enables us to derive the ...
The electronic and geometric structure of [NiFe] hydrogenases studied by theoretical spectroscopy
(2013-05-07)
[NiFe] hydrogenases catalyze the reversible oxidative cleavage of molecular hydrogen at high rates. In the present study, DFT was employed to investigate the geometric and electronic structure of various redox-states of ...
Matching the heterotic string on orbifolds and their resolutions
(2013-08-21)
We study the symmetry breaking mechanism under which a 6d orbifold compactification of the 10d heterotic string turns into a smooth Calabi--Yau compactification. This process is naturally required to preserve N=1 supersymmetry ...
FOXO-abhängige Regulation von Immunabwehr und Lebensspanne in Drosophila melanogaster
(2013-05-22)
Die Regulation der Lebensspanne durch den Insulinsignalweg (IlS) ist evolutionär konserviert und wird vor allem in C. elegans, Drosophila und der Maus untersucht. Es ist eine Reihe von Genen bekannt, die Bestandteile der ......
Molecular Regulation of SATB1 in Regulatory T-cells
(2013-05-07)
In this study we have identified SATB1, a nuclear protein that recruits chromatin-remodeling factors and regulates numerous genes, as a novel effector molecule in Treg cells. Our interest in SATB1 resulted from ......
The response of human myeloid cells to the infection with Listeria monocytogenes
(2013-05-22)
Macrophages and dendritic cells (DC) constitute the first line of defense against invading microorganisms. These myeloid cells have been identified as the major components of the outer ringwall of suppurative granulomas ......