The Faculty of Mathematics and Natural Sciences
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Fachgruppe Biologie (10)
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Fachgruppe Mathematik (154)
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E-Dissertationen (4562)
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Publikationen (0)
Recent Submissions
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Development of an automated RNA capture-SELEX for enriching modular RNA light-up sensors
(2026-06-09)This thesis examines recent advances in selecting and functionalizing RNA aptamers for molecular sensing applications. Two related studies have been carried out: developing a robotic platform for automated RNA aptamer ... -
Intuitive Explainable Artificial Intelligence for Molecular Design
(2026-06-09)With the onset of artificial intelligence (AI), machine learning (ML) approaches have become increasingly embedded into the drug discovery pipeline with the aim of accelerating research and reducing cost. Exemplary ... -
Co-ReaSON: EEG-based Onset Detection of Focal Epileptic Seizures with Multimodal Feature Representations
(2024-05-01)Early detection of an epileptic seizure's onset is crucial to reduce the impact of seizures on the patient's health. The Electroencephalogram (EEG) has been widely used in clinical epileptology for continuous, long-term ... -
A geometric compactification of the moduli space of grafted surfaces
(2026-06-05)In this thesis, we study the degenerations of complex projective structures on an orientable surface S of genus at least two, aiming to describe a compactification of their moduli space and provide a geometric interpretation ... -
Long-distance effects in rare B decays
(2026-06-02)The physics underlying the change of quark flavor provides important constraints on physics beyond our current best understanding. These indirect searches for signs of New Physics require the comparison of high-precision ... -
Enlightening Main Group Chemistry: Development and Synthesis of Novel Chromophores Based on Heavy Pnictogens
(2026-06-02)Owing to their highly tunable photophysical properties, boron difluoride complexes of dipyrrins (BODIPY) have established themselves as versatile chromophores with widespread applications in research areas beyond synthetic ... -
The Role of Afferent Hippocampal to Prefrontal Cortex Projections in a Mouse Model of Alzheimer's Disease
(2026-06-01)Alzheimer's disease is the most common cause of dementia and is marked by progressive cognitive decline. Early dysfunction appears in the hippocampus and later involves the prefrontal cortex. These two brain regions are ... -
Radio and millimeter observations of the environments of young stars undergoing accretion bursts
(2026-05-28)Studying the formation and evolution of Sun-like stars is crucial for understanding the origins of the Solar System. Young stellar objects (YSOs) undergo episodic outbursts that may impact disk chemistry and planet formation. ... -
Metabolic Lipid Tracing in the Rodent Heart
(2026-05-28)Cardiovascular diseases remain the leading cause of death worldwide and represent enormous medical challenge. Therefore, the search for better treatment strategies and markers for early cardiovascular diseases detection ... -
Macrophages in the pathophysiology of myxomatous mitral valve dystrophy
(2026-05-28)Myxomatous mitral valve dystrophy (MVD) is the first cause of mitral valve prolapse (MVP), a common disease affecting 2 to 3 % of the population. The first causal mutation in the <em>FLNA</em> gene (<em>FLNA-P637Q</em>), ... -
Dysregulation of protein translation and sensory function in Drosophila melanogaster autism models
(2026-05-27)Autism spectrum disorders (ASDs) are highly heterogeneous neurodevelopmental conditions affecting 1–2% of children and characterized by impaired social interaction, repetitive behaviors, and sensory abnormalities. Although ... -
Variational methods for the analysis of geometric problems in solid mechanics
(2026-05-26)In this thesis I study geometric problems which commonly arise in material science. The goal of these models is to derive structural properties of the material by describing the time evolution of defects inside the material, ... -
Urban Transformation and Informal Livelihoods: A Battle for Space and the Geographies of Expulsion of Informal E-waste Workers in Accra, Ghana
(2026-05-22)Cities across the world are experiencing rapid urbanisation, bringing complex challenges related to employment, housing, and infrastructure. In response, governments are increasingly implementing large-scale urban ... -
In silico exploration of structural peculiarities of heme-binding proteins
(2026-05-22)Exponential gains in computing and AI have reshaped biochemical research, enabling pathways-level reasoning and atomistic simulation of proteins. Among small-molecule effectors, labile heme is distinctive as it can impair ... -
Community Assembly and Species Coexistence in Sulawesi's Stream Fishes
(2026-05-18)(noch nicht zugänglich / not yet accessible) -
Molecular tools, drugs and conjugates for the modulation of purinergic signal transduction
(2026-05-13)(noch nicht zugänglich / not yet accessible) -
Characterization of Toll-Like Receptor 8 and Its Modulation through Novel Small-Molecule Antagonists
(2026-05-13)Toll-like receptor 8 (TLR8) represents a key endosomal pattern recognition receptor that senses RNA degradation products to initiate proinflammatory signaling in myeloid cells, linking innate immunity to adaptive responses. ... -
Supramolekulare Organisation auf Oberflächen und π-konjugierte Oligomere als funktionale Bausteine
(2026-05-13)Im Rahmen dieser Dissertation wurden Strategien zur gezielten Herstellung und Kontrolle supramolekularer Nanostrukturen auf Oberflächen im Kontext der organischen und supramolekularen Chemie untersucht. Ziel der Arbeit war ... -
Tracing the effects of stellar feedback on molecular gas from simulations to observations
(2026-05-12)The interstellar medium (ISM) is a turbulent, multi-phase medium with a hierarchical structure consisting of molecular clouds (MCs), clumps, and cores. Stars form in dense cores and, over their evolution, inject mass, ... -
A stochastic modelling framework for cancer patient trajectories: combining tumour growth, metastasis, and survival
(2025-05-22)Cancer is a major burden of disease around the globe and one of the leading causes of premature death. The key to improve patient outcomes in modern clinical cancer research is to gain insights into dynamics underlying ...
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