Mathematisch-Naturwissenschaftliche Fakultät: Suche
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Visual analytics methods for shape analysis of biomedical images exemplified on rodent skull morphology
(2017-07-21)
In morphometrics and its application fields like medicine and biology experts are interested in causal relations of variation in organismic shape to phylogenetic, ecological, geographical, epidemiological or disease factors ...
Universelle elliptische Gauß-Summen und der Algorithmus von Schoof
(2017-07-21)
Die vorliegende Arbeit beschäftigt sich mit verschiedenen neuen Ansätzen im Kontext des Punktezählens auf elliptischen Kurven über endlichen Primkörpern mit großer Charakteristik. Sie baut dabei auf der Grundidee von Schoof ...
Concentration Dependent Ion–Protein Interaction Patterns Underlying Protein Oligomerization Behaviours
(2017-07-27)
Most proteins do not exist as monomers. Instead, proteins assemble into oligomeric structures, which range from small dimers to intermediately sized clusters to large polymers. Oligomerization is driven by protein–protein ...
Magnetic Resonance Rheology on Phantoms and Human Brains
(2017-07-05)
In this thesis first systematic measurements on phantoms and human brains using Magnetic Resonance Rheology (MRR) are presented and means to evaluate the acquired data are investigated.
MRR is a novel technique ...
MRR is a novel technique ...
Regulation der Protein-Homöostase durch das Co-Chaperon Tpr2
(2017-05-15)
Die Erhaltung der Protein-Homöostase ist essentiell für die Funktion einer jeden Zelle. Molekulare Chaperone regulieren dabei ein sensibles Gleichgewicht aus Proteinabbau und -faltung. Neusynthetisierte oder fehlgefaltete ...
Functional regions within a Q/N rich prion domain driving prion replication in the mammalian cytosol
(2017-05-15)
Prions are proteinaceous infectious agents that replicate by recruiting and converting homotypic soluble proteins into growing aggregates. Prions in mammals cause transmissible spongiform encephalopthies and are composed ...
The mannose receptor influences antigen-presenting cells by direct interaction with CD45R0
(2017-05-15)
The immune system has to manage the critical decision to induce either immunity or tolerance. Cells that take part in the regulatory processes of the immune system are amongst others antigen presenting cells (APCs), ...
Monitoring structural and physiological properties of crop roots using spectral electrical impedance tomography
(2017-06-09)
Non- or minimally invasive methods are urgently needed to characterize and monitor crop root systems, both on the laboratory and the field scale. Traditional research methods still overwhelmingly rely on manual labor, which ...
The orphan G protein-coupled receptor GPR17: its pharmacology and function in recombinant and primary cell expression systems
(2017-04-26)
The reconstitution of myelin sheaths, so called remyelination, represents an innovative therapeutic goal in multiple sclerosis (MS), the most common inflammatory-demyelinating disease of the central nervous system (CNS). ...
Therapeutic concepts: Proposing a new regulatory pathway for combination therapies
(2017-03-24)
Combinations of different medicinal products are widely use in the medical practice and are in fact essential for the treatment of several diseases. The existing regulation for approval of medicinal products offers only a ...