The Faculty of Mathematics and Natural Sciences: Search
Now showing items 111-120 of 220
Mechanism-based Stratification of Alzheimer's and Parkinson's Disease using Artificial Intelligence
(2021-03-29)
The capacity to generate omics and clinical data in biomedical science is growing exponentially over the past decades. Additionally, recent advances in computational power and analyzing capabilities have resulted in ...
Dispersion-theoretical analysis of ππ and πη rescattering effects in strong three-body decays
(2021-10-08)
Employing dispersion theory to analyse hadronic three-body decays is a classic subject. Based on the fundamental physical principles of analyticity and unitarity, dispersion relations exploit basic theorems of complex ......
Development and Application of Quantum Mechanical Tight-Binding Methods for the Exploration of Chemical Space
(2021-11-17)
This thesis centrally focuses on the systematic exploration of the so-called "chemical space" using fast quantum chemical methods. In computational chemistry any calculation requires a detailed knowledge about a molecules ...
Aptamer-mediated transactivation of transcription utilizing CRISPR/Cas9 and a photoreceptor
(2021-12-16)
In synthetic biology, spatio-temporal control of molecular functions is an essential tool for the investigation and manipulation of cellular processes. The usage of light enables a reversible non-invasive trigger, that ...
Evolution of DNA methylation in insects
(2021-05-21)
DNA methylation, the addition of a methyl group (-CH3) to a genomic cytosine by a DNA methyltransferase, is the most thoroughly studied epigenetic modification across eukaryotes. Functionally, it is associated with the ...
Evaluation and Application of Efficient Quantum Chemical Methods for Sophisticated Simulation of Inorganic Molecular Chemistry
(2021-12-16)
This thesis is devoted to the evaluation and application of efficient quantum chemical methods for the simulation of inorganic molecular chemistry. These methods include dispersion corrected density functional theory (DFT-D) ......
Die vorliegende Arbeit beschäftigt sich mit der Evaluation und Anwendung effizienter quantenchemischer Methoden zur Simulation anorganischer Molekülchemie. Zu diesen Methoden zählen dispersionskorrigierte Dichtefunktionaltheorie ......
Die vorliegende Arbeit beschäftigt sich mit der Evaluation und Anwendung effizienter quantenchemischer Methoden zur Simulation anorganischer Molekülchemie. Zu diesen Methoden zählen dispersionskorrigierte Dichtefunktionaltheorie ......
Investigation of the procoagulant role of labile heme under hemolytic conditions
(2021-07-19)
Severe intravascular hemolysis leads to the excessive release of labile heme into the vascular compartment, thereby overwhelming the heme-binding capacity of the protective heme- scavenging system. As a consequence, labile ...
Structural and functional characterization of TRAP transporters from bacterial pathogens
(2021-08-26)
The class of tripartite ATP-independent periplasmic (TRAP) transporter proteins are wide-spread in the kingdoms of prokaryotes and archaea, where they are responsible for translo-cation of substrates across the cell membrane. ......
Spin Labeling of and EPR Spectroscopic Studies on functional Oligonucleotides
(2021-05-10)
Within the last three decades, the central dogma of molecular biology has been extended
in the sense that RNA is not only the molecule from which the genetic information is
translated into proteins but is involved in ...
Bose-Einstein condensation of erbium atoms for fractional quantum Hall physics
(2021-04-21)
With the advent of ultracold atomic gases experimentally realized by laser cooling techniques nearly 40 years ago, the doors to accessing novel physical behaviour have been opened wide and far. Experimentally, research in ...