The Faculty of Mathematics and Natural Sciences: Search
Now showing items 171-180 of 217
Neuronal and Circuit Architecture Underlying Feeding Behavior in Drosophila
(2021-06-28)
Feeding is elemental for survival and one of the most common activities of animals. Little is known about the organization of neuronal circuits controlling feeding behavior in the cen-tral nervous system. This study maps, ...
Modulation der Gαi1/s-Proteinaktivität durch lineare und makrozyklische Peptide
(2021-07-08)
Die vorliegende Dissertation beschäftigt sich mit der Identifizierung und Charakterisierung von peptidischen Modulatoren für die Gαi/s-Proteinaktivität. Die Ga-Untereinheit heterotrimerer G-Proteine ist eine bedeutende ...
Improved techniques for pulsar data analysis
(2021-09-29)
Pulsars are rapidly rotating, strongly magnetised neutron stars with spin periods ranging from few milliseconds to tens of seconds. They emit beams of electromagnetic radiation that are predominantly detected as periodic ...
Etablierung und Optimierung eines Produktionssystems zur Synthese des alternativen Süßstoffs 5-Ketofruktose in Gluconobacter-Stämmen
(2021-05-21)
Übergewicht, Adipositas und Diabetes sind in der heutigen Gesellschaft längst keine seltenen Krankheiten mehr. In den letzten Jahrzehnten hat die Prävalenz dieser Erkrankungen enorm zugenommen und kann mit einer zuckerreichen ......
Hippocampal network and inhibitory neuron dysfunction in age and disease
(2021-10-25)
Aging and Alzheimer’s disease (AD) are two highly intertwined pathological processes. Indeed, one of the highest risk factors for developing AD is age. Mechanistically, it has been suggested that remodeling of inhibitory ......
Inhibitory Circuits of the CA3-Dentate Gyrus System
(2021-11-04)
Neuronal inhibition is an essential feature of all brain areas. Besides controlling the average rate of neuronal firing, it also controls the precise timing of action potentials and mediates several types of network ...
External Spanier-Whitehead duality for C-spectra and applications to C-homology theories
(2021-07-19)
The thesis constructs a Spanier-Whitehead type duality functor relating finite C-spectra to finite Cop-spectra, where C is a topological index category. We prove that every C-homology theory is given by taking the homotopy ...
Role of presenilins in autophagy and growth factor signaling
(2021-02-08)
Alzheimer's disease is the most common neurodegenerative disease and affects millions of people worldwide. To date, no efficient therapies are known for a cure. As people suffering from diabetes mellitus type 2 have an ...
The Transient Radio Sky: Pulsars and Fast Radio Bursts
(2021-09-17)
This thesis focuses on targeted searches of two radio transients associated with neutron stars (NS): Pulsars and Fast Radio Bursts (FRBs), and the study of their properties over different timescales. Pulsars emit beams of ...
OptoRiboGenetics: Post-transcriptional control of gene expression by light
(2021-08-26)
Gene expression is tightly regulated in mammalian cells at the post transcriptional level and its precise manipulation has proven to be valuable for protein overexpression and gene therapy. Implementation of light-responsive ......
OptoRiboGenetics - Posttranskriptionelle Kontrolle der Genexpression mit Licht
Die Genexpression von Säugetierzellen wird maßgeblich auf post-transkriptioneller Ebene reguliert und das Eingreifen auf ......
OptoRiboGenetics - Posttranskriptionelle Kontrolle der Genexpression mit Licht
Die Genexpression von Säugetierzellen wird maßgeblich auf post-transkriptioneller Ebene reguliert und das Eingreifen auf ......