Mathematisch-Naturwissenschaftliche Fakultät: Suche
Anzeige der Dokumente 21-27 von 27
Regulation of inhibitory synaptic connections and distal neuronal complexity by the Ste20-like kinase Slk
(2022-11-28)
(noch nicht zugänglich / not yet accessible)
I) Characterization of LytR-CpsA-Psr enzymes and their role in Staphylococcus aureus cell wall formation
II) Elucidating the mode of action of Cacaoidin, a novel class V lantibiotic
(2022-04-04)
Antibiotic resistance poses a serious threat to human health, demanding for the discovery and development of antibiotics with resistance-breaking properties. New antibiotics should be sought with the focus on novel chemistry ...
Identification and pharmacological characterization of nucleotide pyrophosphatase/phosphodiesterase-1 (NPP1) and -4 (NPP4) inhibitors
(2022-07-29)
Ectonucleotidases are enzymes involved in different physiological functions and mainly in the regulation of purinergic signaling; in fact, they regulate the duration of purinergic receptor activation by catalyzing the ...
TREM2 modulates differential deposition of post-translationally modified Aβ variants in the brain parenchyma and the vasculature
(2022-08-01)
Alzheimer’s disease (AD) is characterized by the combined presence of extracellular amyloid-beta (Aβ) plaques and intracellular neurofibrillary tangles (NFTs) with abnormally phosphorylated tau (t) protein in the ...
Optogenetische Stimulation des nativen Herzmuskels durch Adeno-assoziierte Virustransduktion von Channelrhodopsin-2
(2022-12-15)
Die Optogenetik ist eine innovative Methode, die die transgene Expression von lichtsensitiven Proteinen verwendet zur elektrophysiologischen oder biochemischen Stimulation von Zellen durch Beleuchtung. Das Beleuchten mit ......
Analysis of reprogramming-associated alterations using an isogenic human stem cell system
(2022-03-04)
Human induced pluripotent stem cells (iPSCs) could provide a valuable tool for the production of specific somatic cell types for disease modeling or cell replacement. Considering the molecular complexity of the reprogramming ...
Engagement of NKT cells during cross-priming enhances the CD8+ T cell response via GATA3 and IL-4/TNFα
(2022-04-21)
(noch nicht zugänglich / not yet accessible)