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Characterization of Ceramide synthase 2 dysfunctions caused by targeted mutations in transgenic mice
(2020-02-10)
Ceramide species are the precursor of sphingolipids, which serve as structural components of biological membranes or are bioactive molecules. In mammals, ceramides are synthesised by a family of ceramide synthases (CerS) ......
3-D Cloud Morphology and Evolution Derived from Hemispheric Stereo Cameras
(2020-02-11)
Clouds play a key role in the Earth-atmosphere system as they reflect incoming solar radiation back to space, while absorbing and emitting longwave radiation. A significant challenge for observation and modeling pose cumulus ...
Lepton Flavor Violation Phenomenology Beyond the Standard Model
(2020-03-12)
Historically, experimental searches for flavor violating processes have been essential for the theoretical developments in Particle Physics. After the detection of neutrino oscillations, the most clear experimental evidence ...
Ryanodine Receptor 2 (RyR2) underlies maintenance and remodeling of dendritic spines
(2020-03-09)
The human brain comprises 1012 neurons that receive, integrate and transmit electrochemical signals. This complex network constantly re-adapts during an animal’s lifetime. All sensed experiences refine neurons via ...
Autophagy and Vesicle Trafficking in Arabidopsis: Emerging Roles of Gamma Secretase Complex Subunits and AP4 Complex
(2020-02-17)
Presenilins are the catalytic component of γ-secretase complex which was first identified in the genetic screens of the patients suffering from the Alzheimer's disease. Macroautophagy is a major route which encompasses ......
Mapping Properties of Bäcklund Transformations and the Asymptotic Stability of Soliton Solutions for the Nonlinear Schrödinger and Modified Korteweg-de-Vries Equation
(2020-02-17)
We consider the cubic Nonlinear Schrödinger Equation (NLS) and the Modified Korteweg-de-Vries Equation (mKdV) in the one-dimensional, focusing case. For the mKdV, we also restrict ourselves to the case of real-valued ...
Nonequilibrium Dynamics of Correlated Fermi Gases
(2020-10-26)
Strongly correlated quantum systems display a myriad of complex, fascinating behaviour. The competition between charge, spin, orbital, or lattice degrees of freedom and their respective energy scales gives rise to rich and ...
Molecular pharmacological analysis of the human MrgD receptor: New insights into signaling
(2021-08-09)
Introduction: MrgD is a member of the MAS-related GPCRs family. It has been proposed to play roles in nociception and cardiovascular control. MrgD has been shown to couple to Gq, Gi, and Gs proteins. The ...
Planning Hybrid Driving-Stepping Locomotion for Ground Robots in Challenging Environments
(2020-02-10)
Ground robots capable of navigating a wide range of terrains are needed in several domains such as disaster response or planetary exploration. Hybrid driving-stepping locomotion is promising since it combines the complementary ...
The enzyme HPGD is critical for regulatory T cell function in adipose tissue
(2020-02-06)
Regulatory T cells (Treg cells) are essential for maintaining immune homeostasis. However, how Treg cells exert their function in tissue specific environments is often unknown. We have found ......