Mathematisch-Naturwissenschaftliche Fakultät: Suche
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Chemoinformatics-Driven Approaches for Kinase Drug Discovery
(2020-01-07)
Given their importance for the majority of cell physiology processes, protein kinases are among the most extensively studied protein targets in drug discovery. Inappropriate regulation of their basal levels results in ...
Probing the Interstellar Medium and Dark Matter with Pulsars
(2020-03-05)
Pulsars are rapidly rotating, highly magnetised neutron stars which emit electromagnetic radiation from their magnetic poles in the form of highly collimated beams. Pulsars are known as a powerful tool to probe the ...
Revealing the Invisible: On the Extraction of Latent Information from Generalized Image Data
(2020-01-08)
The desire to reveal the invisible in order to explain the world around us has been a source of impetus for technological and scientific progress throughout human history. Many of the phenomena that directly affect us ...
Hadron-Hadron Interactions from Nf = 2+1+1 Lattice QCD: The ρ-resonance
(2020-01-07)
In this work the calculation of the ρ resonance's decay parameters with Nf = 2+1+1 flavour lattice QCD is presented. The calculation is performed based on gauge configuration ensembles produced by the ETM ......
DEMS-Messungen zur Magnesiumabscheidung und Auflösung in nichtwässrigen Elektrolyten
(2020-01-13)
In dieser Arbeit werden Elektrolytsysteme mit Magnesiumsalzen untersucht. Die Stabilität und Effizienz der Elektrolyte und die Bildung von flüchtigen Spezies stehen dabei im Fokus, wodurch Rückschlüsse auf die ablaufenden ...
Weak lensing magnification in SpARCS
(2020-02-04)
The growth of large scale structure is one of the fundamental predictions of any cosmological model. Galaxy clusters are the highest peaks in the cosmological matter density field and therefore of prime importance in ...
Disconnected Contributions to Hadronic Processes
(2020-01-06)
Lattice quantum chromodynamics (QCD) is a powerful tool to calculate the dynamics of low-energy, non-perturbative QCD. It has made great strides in numerically evaluating hadronic observables by simulating the interactions ...
Antwortverhalten medullärer Seitenlinienneurone von rheophilen Fischen auf kármánsche Wirbelstraßen
(2020-01-15)
Fische und Amphibien sind mithilfe der mechanosensorischen Seitenlinie in der Lage, Wasserbewegungen und Druckgradienten zu detektieren. Die Detektion dieser Reize erfolgt durch Oberflächenneuromasten auf der Haut der ...
Unraveling TRIM71-mediated RNA regulatory mechanisms during developmental and oncogenic processes
(2020-05-18)
A dysregulation in the tight control of cell proliferation and differentiation severely affects developmental processes, and can lead to oncogenic transformation in the adult organism. The stem cell-specific protein TRIM71 ...
Characterization of cellular functions of the deubiquitinating enzyme OTUD4
(2020-08-10)
Post-translational modification of proteins with ubiquitin influences myriad of cellular processes by affecting protein stability, degradation, localization and protein-protein interactions. Ubiquitin gets transferred to ...