The Faculty of Mathematics and Natural Sciences: Search
Now showing items 191-200 of 213
Relevance of cGAMP-mediated bystander cell activation and cooperation of cGAS and TLR signaling in TREX1-related autoimmunity
(2020-11-05)
The aberrant recognition of endogenous nucleic acids by innate immune sensors can trigger a wide range of autoimmune and autoinflammatory conditions, mediated by type I interferons. Laoss-of-function mutations in the three ......
Bedeutung der cGAMP-vermittelten Bystander-Zellaktivierung und der Kooperation von cGAS- und TLR-Signalwegen bei TREX1-assoziierter Autoimmunität
Entwicklung von Autoinflammation und Autoimmune ......
Bedeutung der cGAMP-vermittelten Bystander-Zellaktivierung und der Kooperation von cGAS- und TLR-Signalwegen bei TREX1-assoziierter Autoimmunität
Entwicklung von Autoinflammation und Autoimmune ......
Historical Biogeography and Macroevolution of the Atacama Desert Flora
(2020-09-17)
Located in northern Chile, the Atacama Desert is not only one of the oldest deserts but also one of the driest places on earth with hyperarid conditions prevailing since the Miocene or earlier. Despite the extreme conditions ...
Pharmacokinetic-pharmacodynamic modeling of antibacterial agents in tissues and body fluids
(2020-11-25)
The aim of this thesis was to assess the pharmacokinetic / pharmacodynamics (PK/PD) of anti-bacterial agents in tissues and body fluids through non-linear mixed effects (NLME) modeling.
In the first project, a ...
In the first project, a ...
Diversity of feeding and pollination strategies of Mesozoic beetles
(2020-08-23)
Beetles (Order: Coleoptera) as the most diverse and successful animals on the earth, comprise about 400,000 species, constituting almost 40% of described insects and a quarter of all animal species. They are distributed ......
In situ observations of reaction and transport phenomena during silicate glass corrosion by fluid-cell Raman spectroscopy: Method development and applications
(2020-07-06)
Borosilicate glass is the preferred material for the immobilization of high-level nuclear waste and an important material for various industries. Silicate glasses, however, are prone to corrosion by aqueous solutions, which ......
Direct lineage programming - a tool to generate and analyze human cortical layer specific neurons
(2020-05-14)
Until recently, lineage commitment and differentiation have been considered to be unidirectional and irreversible. This traditional view has dramatically changed with the advent of cellular reprogramming and direct cell ......
On some Geometric Search Problems: Algorithms, Complexity, Computability
(2020-11-25)
This thesis considers four search problems which are related to or emerge from a geometric context. Each search problem is examined in a separate chapter; these four chapters are framed by an introduction and a conclusion ...
Occlusion and Function of Triconodont Dentitions
(2020-12-18)
Over the last decades, many studies have focused on the tribosphenic molar and its functional aspects because it is considered to be a key innovation in mammalian evolution. Early triconodont dentitions have been examined ...
Impact Assessment of Land-Use Change and Agricultural Treatments on Greenhouse Gas Emissions from Wetlands of Uganda and Tanzania
(2020-02-04)
Wetlands play an important role in global climate regulation as they represent a great global carbon sink. Moreover, wetlands provide optimal conditions for food production and support the livelihoods of many people in ...
Functional in vivo calcium imaging in the hippocampus under healthy and disease conditions
(2020-04-22)
The hippocampus has long been known to be essential for all features of memory processing. Hippocampal function strongly depends on the orchestrated activity of transiently autonomous neuronal populations that create the ......