The Faculty of Mathematics and Natural Sciences: Search
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Pharmacokinetics of Antidepressants and Lithium: Variability and Clinical Implication for Individual Dose Adaptation
(2003)
Depression is the most frequent mental disorder occuring in 17% of the European population and its impact is assumed to grow in the next decades. Optimal treatment necessitates long-term administration of antidepressants ...
Pharmacokinetics and pharmacodynamics of intraventricularly administered etoposide in brain tumour patients
(2007)
In order to find the optimal dosage regimen of intraventricularly (ivc) administered etoposide, pharmacokinetic disposition of etoposide in cerebrospinal fluid was investigated in 22 patients (119 cycles) after intraventricular ...
Klinische Untersuchungen zur Dosis-Konzentrations-Effektbeziehung von Oxaliplatin
(2006)
Oxaliplatin ist nach Cisplatin und Carboplatin der dritte klinisch eingesetzte Platinkomplex. Dosislimitierend ist eine kumulative periphere Neurotoxizität. Oxaliplatin wird überwiegend in Kombinationstherapien bei ...