Augenklinik: Publikationen
Recent Submissions
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Spatially Resolved Association of Structural Biomarkers on Retinal Function in Non-Exudative Age-Related Macular Degeneration Over 4 Years
(2024-04-30)<strong>PURPOSE.</strong> To longitudinally assess the impact of high-risk structural biomarkers for natural disease progression in non-exudative age-related macular degeneration (AMD) on spatially resolved mesopic and ... -
The Spectrum of Functional, Structural and Patient-Reported Outcomes in Intermediate Age-Related Macular Degeneration: A MACUSTAR Study Report
(2025-02-03)<em><strong>Introduction:</strong></em> There is an unmet medical need for therapies in intermediate age-related macular degeneration (iAMD). The prospective European multi-center cohort study MACUSTAR validates structural, ... -
Characterization of the disorganization of the inner retinal layers in diabetics using increased axial resolution optical coherence tomography
(2025-01-13)<strong>Purpose:</strong> To compare a novel high-resolution optical coherence tomography (OCT) with improved axial resolution (High-Res OCT) with conventional spectral-domain OCT (SD-OCT) with regard to their capacity to ... -
Retro Mode Imaging for Detection and Quantification of Sub-RPE Drusen and Subretinal Drusenoid Deposits in Age-Related Macular Degeneration
(2024-07-15)<strong>Background:</strong> Drusen and drusenoid deposits are a hallmark of age-related macular degeneration (AMD). Nowadays, a multimodal retinal imaging approach enables the detection of these deposits. However, ... -
Assessment of local sensitivity in incomplete retinal pigment epithelium and outer retinal atrophy (iRORA) lesions in intermediate age-related macular degeneration (iAMD)
(2024-07-09)<strong>Objective</strong> Lesions of incomplete retinal pigment epithelium and outer retinal atrophy (iRORA) are associated with disease progression in intermediate age-related macular degeneration (AMD). However, the ... -
Mass Spectrometry-Based Profiling of Histone Post-Translational Modifications in Uveal Melanoma Tissues, Human Melanocytes, and Uveal Melanoma Cell Lines: A Pilot Study
(2024-02-13)<strong>PURPOSE.</strong> Epigenetic alterations in uveal melanoma (UM) are still neither well characterized, nor understood. In this pilot study, we sought to provide a deeper insight into the possible role of epigenetic ... -
Sub-cone visual resolution by active, adaptive sampling in the human foveola
(2024-10-29)The foveated architecture of the human retina and the eye’s mobility enable prime spatial vision, yet the interplay between photoreceptor cell topography and the constant motion of the eye during fixation remains unexplored. ... -
Reliability of Retinal Layer Annotation with a Novel, High-Resolution Optical Coherence Tomography Device: A Comparative Study
(2023-03-31)Optical coherence tomography (OCT) enables in vivo diagnostics of individual retinal layers in the living human eye. However, improved imaging resolution could aid diagnosis and monitoring of retinal diseases and identify ...
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