Institut für Molekulare Medizin und Experimentelle Immunologie (IMMEI)

 

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  • Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury 

    Hackstein, Carl-Philipp; Spitzer, Jasper; Symeonidis, Konstantinos; Horvatic, Helena; Bedke, Tanja; Steglich, Babett; Klein, Sabine; Assmus, Lisa; Odainic, Alexandru; Szlapa, Jennifer; Kessler, Nina; Beyer, Marc; Schmithausen, Ricarda; Latz, Eicke; Flavell, Richard; Garbi, Natalio; Kurts, Christian; Kümmerer, Beate; Trebicka, Jonel; Roers, Axel; Huber, Samuel; Schmidt, Susanne; Knolle, Percy; Abdullah, Zeinab (2023-03-02)
    <strong>Background & Aims:</strong> Patients with chronic liver disease (CLD), including cirrhosis, are at increased risk of intractable viral infections and are hyporesponsive to vaccination. Hallmarks of CLD and cirrhosis ...