E-Dissertationen: Browsing E-Dissertationen by Author "Garbi, Natalio"
Now showing items 1-11 of 11
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Chronic Helminth Infection Ameliorates Colitis via ***** regeneration program
Kazakov, Alexander (2022-03-07)(noch nicht zugänglich / not yet accessible) -
Essential and complementary function of dendritic cell subsets during immunotherapy
Dähling, Sabrina (2020-03-11)T lymphocytes are critical components of the adaptive immune system that protects us against a variety of infections. However, during chronic infections such as with HIV, HCV and HBV as well as cancers, T cells become ... -
Immune defense mechanisms against Legionella longbeachae
Scheiding, Victoria Madeleine (2020-01-30)The pulmonary epithelial barrier is the first line of defense against pathogens invading the lungs. If those are able to overcome this first barrier, myeloid cells of the innate immune system are instrumental for the ... -
Immunogener Tumorzelltod von Ovarialkarzinomzellen durch die gezielte Aktivierung der Virus-Sensoren RIG-I und MDA-5 – Etablierung eines Immuntherapiekonzepts im Mausmodell
tho Pesch, Carola (2016-06-30)Tumorzellen lösen häufig keine wirksame, gegen den Tumor gerichtete Immunantwort aus. Im Gegensatz hierzu wird die Anwesenheit von Viren umgehend durch das angeborene Immunsystem erkannt, was letztendlich zur gezielten ... -
Impact of chronic liver inflammation on adaptive immune responses to viral infection
Assmus, Lisa Mareike (2020-03-11)A common complication in patients suffering from chronic liver inflammation and fibrosis is the enhanced susceptibility to viral infections and weak responses to vaccination, which are associated with significant co-morbidities. ... -
Legionnaires' Disease - the impact of cigarette smoke and functional lung recovery
Fleischmann, Markus (2023-02-14)Legionnaires’ Disease is a severe type of pneumonia most commonly caused by the bacterial species <em>Legionella pneumophila</em> and <em>Legionella longbeachae</em>. Epidemiological studies show that cigarette smoke is a ... -
Programmed cell death regulation during Salmonella Typhimurium infections
Engel, Sven Julian (2024-01-18)Programmed cell death (PCD) is a highly regulated process that is vital for the development and homeostasis of multicellular organisms. It functions as an essential mechanism to remove dispensable or unfavourable cells in ... -
Return of the first inflammasome: Elucidation of NLRP1 inflammasome activation by p38-mediated phosphorylation and ubiquitination
Jenster, Lea-Marie (2024-01-30)The assembly of inflammasomes is linked to the detection of pathogens and other danger signals by intracellular pattern-recognition receptors of the mammalian innate immune system. The human inflammasome sensor NLRP1 is ... -
The role of cytohesins in the regulation of immune responses
Solomatina, Anastasia (2020-02-17)Cytohesins are guanine nucleotide exchange factors for adenosine diphosphate ribosylation factor (Arf) proteins and promote the switch of Arfs to the active GTP-bound form. Cytohesins have been shown in different <em>in ... -
The role of T cell help in shaping Dendritic Cell function
Gressier, Elise (2020-02-07)CD8<sup>+</sup> T cell priming depends on antigen presentation by dendritic cells (DCs) and their capacity to communicate contextual cues associated with antigen acquisition. DCs often also require additional signals from ... -
Role of the chemokines CCL17 and CCL22 in bacterial infection and IL-33-induced immune responses
Thiem, Manja Wibke (2023-11-24)The chemokines CCL17 and CCL22 are primarily expressed by dendritic cells (DC) and macrophages. Both chemokines share the receptor CCR4, which is expressed on DC and macrophages as well as on a variety of different T cell ...