E-Dissertationen: Browsing E-Dissertationen by Author "Gebhardt, Thomas"
Now showing items 1-3 of 3
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Development of a CRISPR/Cas9 based RiboTag strategy to identify regulators of melanoma immune interaction
Kretzmer, Freya Maria (2023-11-09)The development of immunotherapy approaches has revolutionised the field of melanoma treatment by prolonging the survival of patients. Nevertheless, a significant proportion of patients either do not respond to immunotherapy ... -
Melanoma immunosurveillance by CD4+ T cells
Bawden, Emma (2021-07-05)The immune system can recognise and control cancer cells in a process termed cancer immunosurveillance. There is increasing evidence that CD4<sup>+</sup> T cells play an important role in melanoma immunosurveillance but ... -
Modelling melanoma control by immunotherapy and tissue-resident memory T cells using CRISPR/Cas9-based approaches
Effern, Maike (2020-02-03)In recent years, immunotherapy has demonstrated remarkable efficacy in the treatment of metastatic melanoma due to the development of T cell-based therapies such as checkpoint inhibitors or adoptive T cell transfer therapy ...