E-Dissertationen: Browsing E-Dissertationen by Subject "T cells"
Now showing items 1-3 of 3
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Nanoparticle delivery of molecular agents to tackle HIV latency
Ali, Abdalla Abbas Jafer (2022-09-16)Antiretroviral therapy (ART) effectively suppresses HIV replication in people living with HIV (PLWH), but treatment is lifelong. The persistence of long-lived, latently infected resting CD4<sup>+</sup>T cells is a significant ... -
Return of the first inflammasome: Elucidation of NLRP1 inflammasome activation by p38-mediated phosphorylation and ubiquitination
Jenster, Lea-Marie (2024-01-30)The assembly of inflammasomes is linked to the detection of pathogens and other danger signals by intracellular pattern-recognition receptors of the mammalian innate immune system. The human inflammasome sensor NLRP1 is ... -
The role of cytohesins in the regulation of immune responses
Solomatina, Anastasia (2020-02-17)Cytohesins are guanine nucleotide exchange factors for adenosine diphosphate ribosylation factor (Arf) proteins and promote the switch of Arfs to the active GTP-bound form. Cytohesins have been shown in different <em>in ...