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MAIT cell diversity, function and impact on dendritic cells
(2020-04-01)
T cells represent an important component of the immune system. Whilst early studies were largely focused on the role of conventional CD8+ and CD4+ T cells that recognize peptide-antigens in association ...
Function and diversity of myeloid cells during chronic inflammation in non-lymphoid organs
(2020-03-10)
Different immune cells play a major role in maintaining tissue homeostasis, tissue repair but also in inflammation. Tissue integrity is mainly controlled by tissue regulatory T cells (Tregs), type 2 innate ...
Essential and complementary function of dendritic cell subsets during immunotherapy
(2020-03-11)
T lymphocytes are critical components of the adaptive immune system that protects us against a variety of infections. However, during chronic infections such as with HIV, HCV and HBV as well as cancers, T cells become ...
Functional and cellular heterogeneity of the myeloid cell system
(2020-11-09)
Cells of the myeloid lineage form the innate part of the immune system and are characterized by a high level of functional plasticity, which is required to address the diverse set of functions of these mononuclear cells. ...