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Characterization of a novel multiprotein complex downstream of the cytosolic nucleic acid sensors cGAS and RIG-I
(2021-08-30)
Detection of viral nucleic acids by specialized PRRs of the innate immune system triggers the expression of type I IFNs, a hallmark of antiviral defense. In vertebrates, the cGAS-STING pathway and the RLR-MAVS pathway have ......