E-Dissertationen: Search
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Ribosome profiling of selenoproteins in vivo reveals consequences of pathogenic Secisbp2 missense mutations: The establishment of translating ribosome affinity purification
(2020-11-04)
Recoding of in-frame UGA/Seccodon in selenoproteins requires a complex translational machinery. The core of this event is the interaction between selenocysteine insertion sequence (SECIS element) in the 3’UTR of ...
Investigating the ability of RIG-I agonists to provide protection in mouse and ferret models of respiratory virus infection
(2022-05-17)
Respiratory infections caused by influenza A virus (IAV) or respiratory syncytial virus (RSV) lead to substantial morbidity and mortality. Treatment options are limited and there is urgent need for the development of ......
Impact of G-Quadruplexes on DNA damage and repair supported by the protein Zuo1 in Saccharomyces cerevisiae
(2025-01-09)
The secondary structures known as G-Quadruplexes (G4s) play crucial roles in regulating biological processes such as replication, transcription, and DNA repair by folding and unfolding within specific regions of DNA. ......