E-Dissertationen: Search
Now showing items 1-5 of 5
Inducing immunity to liver stage malaria through endogenous tissue resident memory cells
(2020-12-16)
Tissue-resident memory CD8 T (TRM) cells provide effective tissue surveillance and can respond rapidly to infection due to their strategic location. Within the liver, TRM cells can induce effective protection against ...
Low molecular weight polysialic acid prevents lipopolysaccharide-induced inflammatory dopaminergic neurodegeneration in humanized SIGLEC11 transgenic mice
(2021-07-13)
Parkinson’s disease is one of the most common neurodegenerative diseases in the elderly population, with a pathophysiology linked to neuroinflammation, complement activation and oxidative damage. Soluble polysialic acid ...
Opioide im Vergleich: Effektivität und Sicherheit von Oxycodon und Piritramid zur Analgesie bei Mittelohreingriffen
(2021-10-18)
Hintergrund: Eine rein intravenöse Opioidtherapie ist mit zusätzlichem Material-, Organisations-, Personal- und Ressourcenaufwand sowie einem erhöhtem Risiko an Nebenwirkungen und potenziell notwendigen ...
Lipid droplet formation drives pathogenic ILC2 responses in airway inflammation
(2020-06-08)
The Western world is affected by a dramatic increase of chronic inflammatory diseases like asthma, Crohn’s disease and psoriasis. Innate lymphoid cells (ILC) play an important role in the control and maintenance of barrier ...
Nucleic acid sensing in CD4 T cells during HIV-1 and other viral infections
(2021-10-15)
Viruses are small intracellular parasites and use the host cell’s biosynthesis machinery to replicate and spread. Therefore, viral particles incorporate structures that are similar to the ones that naturally occur within ...