Faculties of University Bonn: Search
Now showing items 91-100 of 360
A Pilot Study to Identify Sources of Variability in 5-Fluorouracil Pharmacokinetics and Toxicity
(2007)
The aims of this study were to characterise pharmacokinetics of 5-FU and its main metabolite (5-FUH2) and to quantify factors of influence on pharmacokinetics as well as to identify factors influencing adverse events and ...
Stereoselektive Diolsynthese mit Lyasen und Oxidoreduktasen: Entwicklung eines kontinuierlichen Verfahrens
(2007)
Optisch aktive vicinale Diole stellen wichtige Vorläufermoleküle für die Synthese pharmazeutisch interessanter Wirkstoffe dar. Im Rahmen der Dissertation konnte eine stereoselektive enzymatische Synthese aller vier möglichen ...
Automatic classification of grassland herbs in close-range sensed digital colour images
(2007)
The broad-leaved dock (Rumex obtusifolius L. (RUMOB)) is one of the most harmful and persistent weed species on European grassland and it has been spread into the temperate grassland regions throughout the world. Large dry ......
Stochastic Interacting Particle Systems and Nonlinear Partial Differential Equations from Fluid Mechanics
(2007)
We derive stochastic particle approximations for two nonlinear partial differential equations from fluid mechanics: the porous medium equation and the three-dimensional Navier-Stokes equation. We associate interacting ...
Vergleichende Untersuchungen zur Neuro- und Verhaltensbiologie infrarotsensitiver pyrophiler Käfer
(2007)
Im Rahmen dieser Arbeit wurden elektrophysiologische und neuroanatomische Untersuchungen an den pyrophilen Käferarten Acanthocnemus nigricans und Melanophila acuminata (bzw. Melanophila cuspidata) durchgeführt. Das Verhalten ...
Application of photometric redshifts on the correlation properties of galaxies and matter
(2007)
In the past years cosmology, the science of the universe as a whole, has seen tremendous progress. The Lambda-Cold-Dark-Matter scenario is widely accepted as the standard model of cosmology describing the evolution of the ...
Investigation and Optimisation of the Presster: A Linear Compaction Simulator for Rotary Tablet Presses
(2007)
Tablets are currently the most frequently used pharmaceutical dosage form. Development of new tablet formulations is performed on both eccentric and lab scale rotary tablet presses.
Differences in the working principle ...
Differences in the working principle ...
Humane saure Ceramidase: Baculovirus-Expression, Prozessierung, Reinigung, Charakterisierung und Strukturanalyse mittels MALDI-TOF und ESI-Massenspektrometrie
(2007)
Die humane saure Ceramidase katalysiert den letzten Schritt des lysosomalen Sphingolipid-Abbaus, die Hydrolyse von Ceramid zu Sphingosin und Fettsäure. Mutationen im Gen der sauren Ceramidase führen zur Farberschen Krankheit. ...
Regulatory mechanisms in cross-presentation in vivo
(2007)
Dendritic cells can present exogenous antigen to CD8 T cells using a mechanism termed cross-presentation. This mechanism is important for immune responses against tumors, viruses, intracellular pathogens and autoantigens ...
Subtypspezifische Hemmung einzelner, humaner, rekombinanter T-Typ-Calcium-Kanäle durch das Inhalationsnarkotikum Distickstoffmonoxid (Lachgas) als Ansatzpunkt für ein neues analgetisches Wirkprinzip
(2007)
Es wurde untersucht, ob das Inhalationsnarkotikum Distickstoffmonoxid rekombinante, humane, spannungsabhängige CaV3.2 T-Typ Calcium-Kanäle subtypspezifisch auf Einzelkanalebene hemmt. Eine solche Interaktion wurde im ...