Fakultäten der Universität Bonn: Suche
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Insights into Biomolecular Structure from Theoretical Spectroscopy
(2011-11-29)
The first part of the present PhD thesis is concerned with the reaction mechanism of Cytochrome P450 NO reductase. Two important aspects of this enzyme are studied. 1) The structural and electronic nature of the key ......
Novel and Bioactive Natural Products from the Marine-Derived Endophytic Fungi: Coniothyrium cereale, Phaeosphaeria spartinae and Auxarthron reticulatum
(2011-10-28)
The main goal of this study was to discover novel natural products with pharmacological potential by employing various biotechnological methods. Marine fungi have been identified as a promising resource for such molecules. ...
Development of pharmacological modulators for the orphan G protein-coupled receptor GPR17 and their application for the investigation of molecular signal transduction pathways
(2011-11-29)
In order to discover a set of tools suitable to be employed in its in vitro characterization, the recently deorphanized G protein coupled receptor GPR17 was investigated by using different classical second messenger assays ...
Vector bundles on degenerations of elliptic curves and Yang-Baxter equations
(2011-11-15)
In this thesis, we study connections between vector bundles on degenerations of elliptic curves and the classical, quantum and associative Yang-Baxter equation. Let g denote n by n traceless matrices and let U denote the ...
Evaluation of Wolbachia depletion after antibiotic treatment using real-time PCR in Onchocerciasis and Lymphatic Filariasis, and analysis of genetic associations in Lymphatic Filariasis
(2011-11-15)
Two of the major filarial infections, onchocerciasis and LF, affect > 150 million people. Currently, control programs use yearly mass application of drugs that mainly kill microfilaria (Mf) with the aim to prevent uptake ...
Single molecule tracking with light sheet microscopy
(2011-11-11)
The work presented here concentrates on light sheet based fluorescence microscopy (LSFM) and its application to single molecule tracking.
In LSFM the sample is illuminated perpendicular to the detection axis with a ...
In LSFM the sample is illuminated perpendicular to the detection axis with a ...
Erzeugung und Charakterisierung eines Hepatoma-derived Growth Factor (HDGF) -defizienten Mausmodells
(2011-09-19)
Der Hepatoma-derived growth factor (HDGF) bildet zusammen mit den ihm verwandten Proteinen (HRP-1-4 und LEDGF) eine Familie großer, proteinerger Wachstumsfaktoren. Aufgrund seiner ausgeprägten Expression während der ......
Mobilität endogener mRNA im chromatinfreien Nukleoplasma der Speicheldrüsenzellkerne von Chironomus tentans
(2011-07-26)
In eukaryotischen Zellen ist fast die gesamte genetische Information in Form chromosomaler DNA im Zellkern gespeichert, während die molekulare Maschinerie zur Translation ausschließlich cytoplasmatisch lokalisiert ist. Der ...
Study of top-quark pair cross-section measurement in the dilepton channel with the ATLAS detector at the LHC
(2011-09-16)
The top quark is the heaviest of the known fundamental particles in the Standard Model (SM) with a mass of 173.3±1.1GeV. It is the sixth quark in the SM and the weak isospin partner of the bottom quark. Properties such as ......
Studies into tau reconstruction, missing transverse energy and photon induced processes with the ATLAS detector at the LHC
(2011-10-11)
The ATLAS experiment is currently recording data from proton-proton collisions delivered by CERN's Large Hadron Collider. As more data is amassed, studies of both Standard Model processes and searches for new physics beyond ......