Faculties of University Bonn: Search
Now showing items 21-30 of 86
Search for exosomes in NG2-glial cells
(2022-02-17)
NG2-glial cells is an abundant and widely distributed subtype of glia, featuring properties not typically associated with mature glial cells, such as the ability to receive synaptic input from neurons, or adult proliferation. ...
Gating of the Hv1 proton channel
(2022-03-28)
Hv1 is a voltage-gated proton channel, which is involved in the regulation of the intracellular pH (pHi) in immune cells. Among the voltage-gated ion channels, Hv1 is unique because it lacks a classical pore domain and its ...
Biochemical and Structural Characterization of β-Hydroxylases in Non-Ribosomal Peptide Biosynthesis
(2022-02-02)
Hydroxylases are essential in the biosynthesis of natural products by functionalization of building blocks, which derive from primary metabolism. They provide hydrophily for specific interactions or enable further ...
Functional impact of Kir4.1 channels in hippocampal NG2 glia on neuronal plasticity and behavior
(2020-08-25)
NG2 glia represents the 4th type of CNS glial cells. In white matter, most of them differentiate into myelinating oligodendrocytes but in grey matter a majority retains their NG2 phenotype throughout life. Intriguingly, ...
Interesse an Pflanzen fördern: Eine Design Based Research-Studie mit Kindern und Jugendlichen
(2022-01-27)
Obwohl Pflanzen für unsere Ökosysteme unverzichtbar sind, ist das Interesse an diesen Lebewesen bei vielen Menschen gering. Die Förderung des Interesses an Pflanzen scheint von besonderer Bedeutung, zumal das Interesse an ...
Impact of chronic liver inflammation on adaptive immune responses to viral infection
(2020-03-11)
A common complication in patients suffering from chronic liver inflammation and fibrosis is the enhanced susceptibility to viral infections and weak responses to vaccination, which are associated with significant co-morbidities. ...
Immune defense mechanisms against Legionella longbeachae
(2020-01-30)
The pulmonary epithelial barrier is the first line of defense against pathogens invading the lungs. If those are able to overcome this first barrier, myeloid cells of the innate immune system are instrumental for the ......
Impact of UGT1A polymorphisms on inflammation and fibrogenesis in a humanized transgenic mouse model
(2020-07-07)
Fibrogenesis represents a highly dynamic scarring response of the liver resulting from different causes of hepatic injury. A key process capable of activating a broad array of profibrogenic pathways is oxidative stress. ...
Science und Fiction - Entwicklung und Evaluation eines Konzepts zum interesseförderlichen Einsatz von kreativen Schreibwerkstätten im Biologieunterricht
(2020-08-07)
Interesse wird als wichtige Voraussetzung für die Dynamik und Qualität von Bildungsprozessen angesehen und gilt als einer der Vorläufer einer generellen, selbstbestimmten Lernmotivation. Im Mittelpunkt dieser vorrangig ...
Changes of inner teat morphology caused by the milking process and by incomplete milking during dry-off as assessed by innovative technologies
(2020-03-03)
In dairy farming, the timing of the lactation cycle and the way of milk removal differ considerably from the natural conditions. Ensuring good health and wellbeing of farm animals is of great interest from both an economic ...