Faculties of University Bonn: Search
Now showing items 591-600 of 642
Rationales Design und Aufbau DNA- und Fluorophor-markierter chemischer Sonden für G-Protein-gekoppelte Rezeptoren
(2021-03-04)
Die vorliegende Dissertation umfasst die Synthese von Wirkstoff-Molekülen sowie fluoreszenzmarkierten und Oligonukleotid-gebundenen Wirkstoffen, die als Sonden zur Untersuchung von G-Protein-gekoppelten Rezeptoren (GPCRs), ...
Synthesis, optimization, and characterization of chromen-4-one and 1,7-phenanthroline derivatives as ligands for the orphan G protein-coupled receptors 35 and 84
(2021-06-21)
G protein-coupled receptors (GPCRs) are ideal drug targets. Their characteristic tissue distribution, marked ligand specificity, and their roles in countless (patho)physiological processes are being exploited by more than ...
Neue Phenylen-basierte molekulare Speichenräder
(2023-08-21)
(noch nicht zugänglich / not yet accessible)
Diastereoselektive Titanocen(III)-Katalyse – Synthese benzylischer 1,3-Dioxolane und 1,3-Oxazolidine
(2023-09-14)
(noch nicht zugänglich / not yet accessible)
Metall-Luft Batterien: RRDE- und DEMS-Messungen zur Sauerstoffreduktion und Entwicklung in nichtwässrigen Alkali- und Erdalkali-haltigen Elektrolyten
(2023-11-09)
Bei der Sauerstoffreduktion und -entwicklung im Na+/DMSO und im Li+-Na+ Mischelektrolyten sind die Elektrodenmaterialien Pt und Au verwendet worden. In reinem Na+-Elektrolyten ...
Response properties of open shell molecules and their application in studies of electron paramagnetic resonance parameters
(2023-11-20)
The synergy of experimental and theoretical investigations is highly powerful and is therefore utilized to gain a deeper understanding of (bio)chemical processes. Especially, molecular spectroscopy provides detailed ...
On the importance of meteorological parameters in processes affecting the chemical composition of the tropsphere
(2022-12-22)
Investigating the interaction of meteorology and chemistry in the troposphere is important for the identification of the processes which drive the evolution of tropospheric composition in a changing climate. It does not ...
Investigating the ability of RIG-I agonists to provide protection in mouse and ferret models of respiratory virus infection
(2022-05-17)
Respiratory infections caused by influenza A virus (IAV) or respiratory syncytial virus (RSV) lead to substantial morbidity and mortality. Treatment options are limited and there is urgent need for the development of ......
Identification and pharmacological characterization of nucleotide pyrophosphatase/phosphodiesterase-1 (NPP1) and -4 (NPP4) inhibitors
(2022-07-29)
Ectonucleotidases are enzymes involved in different physiological functions and mainly in the regulation of purinergic signaling; in fact, they regulate the duration of purinergic receptor activation by catalyzing the ...
Selbstassemblierte Monolagen organischer Moleküle auf Festkörperoberflächen
(2022-08-22)
Im Rahmen der vorliegenden Arbeit wurden selbstassemblierte Monolagen organischer Moleküle an der Fest-Flüssig-Grenzfläche von Graphit mittels Rastertunnelmikroskopie untersucht. Die Arbeit verfolgte das Ziel, das Verständnis ......