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Second-line and third-line therapy with nanoliposomal irinotecan (nal-IRI) in pancreatic cancer: a single-center experience and review of literature
(2023-02-15)
Background: Prognosis of patients with pancreatic cancer is still extremely poor. First-line palliative therapies with FOLFIRINOX or gemcitabine/nab-paclitaxel have been established in the last decade. In the second-line, ...
Exploring the Applicability of General Dietary Recommendations for People Affected by Obesity
(2023-03-25)
(1) Obesity has emerged as a major public health challenge with increasing prevalence globally. The General Dietary Behavior Inventory (GDBI) was developed based on official dietary recommendations. However, little is known ...
Reliability of Retinal Layer Annotation with a Novel, High-Resolution Optical Coherence Tomography Device: A Comparative Study
(2023-03-31)
Optical coherence tomography (OCT) enables in vivo diagnostics of individual retinal
layers in the living human eye. However, improved imaging resolution could aid diagnosis and
monitoring of retinal diseases and identify ...
Small Changes in Patient Arrival and Consultation Times Have Large Effects on Patients' Waiting Times: Simulation Analyses for Primary Care
(2023-01-18)
(1) Background: Workflows are a daily challenge in general practices. The desired smooth
work processes and patient flows are not easy to achieve. This study uses an operational research
approach to illustrate the general ...
Parameters Associated with the Required Drug Dose of Intravenous Immunoglobulin in Stable Chronic Inflammatory Demyelinating Polyradiculoneuropathy
(2023-03-10)
Background: Intravenous immunoglobulin (IVIg) is efficient and one of very few treatment
options for patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).
However, finding the optimal dose of ...
Additive prognostic impact of the cerebrospinal fluid arginine/ornithine ratio to established clinical scores in aneurysmal subarachnoid hemorrhage
(2023-04-14)
Cerebrospinal fluid (CSF) metabolites are increasingly recognized as prognostic
factors in aneurysmal subarachnoid hemorrhage (SAH). The CSF arginine/
ornithine ratio (Arg/Orn) was shown to predict cerebral vasospasms ...
Cost-effectiveness and Quality of Specialized and Routine Care in a German Cohort of Patients with Chronic Pruritus
(2023-04-21)
Chronic pruritus is a prevalent interdisciplinary symptom with a strong influence on health-related quality of life. Patients need extensive diagnostics and long-term treatment. This retrospective and prospective cohort ...