Mathematisch-Naturwissenschaftliche Fakultät: Suche
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Functional in vivo calcium imaging in the hippocampus under healthy and disease conditions
(2020-04-22)
The hippocampus has long been known to be essential for all features of memory processing. Hippocampal function strongly depends on the orchestrated activity of transiently autonomous neuronal populations that create the ......
Geometry of random 3-manifolds
(2020-01-31)
We study random 3-manifolds, as introduced by Dunfield and Thurston, from a geometric point of view. Within this framework, work of Maher allows us to equip a typical random 3-manifold with a canonical geometric structure, ...
Characterization and application of fusogenic liposomes
(2020-02-03)
Conventional drug delivery strategies use the endocytic pathway to introduce biomolecules like proteins, DNA, or antibiotics into living cells. The main disadvantage of endocytic uptake is the quick intercellular degradation ......
The role of diacylglycerol acyltransferase 1 in hepatic medium-chain fatty acid metabolism
(2020-01-28)
Fatty acids form a class of important biomolecules, serving as essential elements of lipid molecules. Stored in triacylglycerol (TAG), the main constituent of plant oils and animal fats, they from an inseparable part of ......
Low Dimensional Gauge Theories and Quantum Geometry
(2020-10-14)
This thesis explores the connection between supersymmetric gauge theories on curved spaces of dimensions two and three and geometries that arise in string theory. It does so by studying quantum field theoretic objects such ......
Creld1 controls T cell homeostasis in mouse and human
(2020-07-07)
Cysteine-rich with EGF-like domains 1 (Creld1) was recently found to be fundamental for the VEGF-mediated activation of NFATc1 during heart development. Creld1 complete KO in mice is lethal due to developmental problems ...
Λ(1405) photoproduction with the BGO-OD experiment
(2020-05-14)
The Λ(1405) has been considered for many years a candidate for an unconventional hadronic state.
Being difficult to understand within the framework of a three valence quark, constituent quark model,
models explicitly ...
Beiträge zur Totalsynthese von Lysolipin I
(2020-06-12)
Die vorliegende Dissertation behandelt Studien zur Totalsynthese des Sekundärmetabolits Lysolipin I (1), eines der höchst-oxidierten, aromatischen Polyketide. Der heptazyklische Kern dieses potenten Antibiotiukums beinhaltet ...
Studien zur Total- und Biosynthese von PR Toxin
(2020-03-06)
Diese Arbeit beschäftigt sich mit dem Pilzgift PR Toxin, welches aus Penicillium roqueforti isoliert werden kann. Es wurden einerseits drei Ansätze für eine Totalsynthese entwickelt und andererseits grundlegende Arbeiten ...
Fast, Accurate and Steerable Segmentation of Drusen in Optical Coherence Tomography
(2020-10-05)
Age-related macular degeneration (AMD) is known to be the leading cause for blindness in developed countries. One of the early appearing biomarkers of AMD are drusen that develop between the retinal pigment epithelium (RPE) ...