The Faculty of Mathematics and Natural Sciences: Search
Now showing items 421-430 of 583
Antibiotic mechanisms of invertebrate and mammalian defensins
(2013-02-19)
Multicellular organisms defend themselves against infectious microorganisms by producing a wide array of antimicrobial peptides referred to as host defence peptides (HDPs). These evolutionary ancient peptides are important ...
Rapid astrocyte morphology changes during epileptogenesis in the rodent hippocampus
(2017-05-15)
In the past decades astrocytes have been demonstrated to play an important role in physiological brain processes but also neurodegenrative diseases. Their characteristic morphology allows them to closely contact neurons. ...
Unravelling mechanisms causing astrocytic uncoupling in epilepsy
(2017-10-06)
The dynamic regulation of connexins throughout its life cycle has profound impact on the level of gap junctional coupling in astrocytes. Astrocytic uncoupling in epilepsy can be viewed in the context of modifications in ...
Organization and function of signaling molecules in sperm
(2017-09-15)
Successful fertilization depends on the ability of sperm to locate the egg. Sperm from different species rely on diverse signaling components to gather chemical and physical cues and transduce them into a behavioral swimming ......
Um die Eizelle zu befruchten, müssen die Spermien die Eizelle zunächst lokalisieren. Dabei helfen ihnen unterschiedliche chemische oder physikalische Signale auf dem Weg zur Eizelle, die dann das Schwimmverhalten der ......
Um die Eizelle zu befruchten, müssen die Spermien die Eizelle zunächst lokalisieren. Dabei helfen ihnen unterschiedliche chemische oder physikalische Signale auf dem Weg zur Eizelle, die dann das Schwimmverhalten der ......
Peroxin3, a newly identified regulator of melanocyte development and melanosome biogenesis in zebrafish Danio rerio
(2017-04-20)
Previous efforts aimed to understand the consequences of a dysregulated control of peroxisome biogenesis and of the dynamics of peroxisomal matrix proteins. Nevertheless, previous publications did not fill the existing gap ...
Molecular mechanisms of extracellular matrix dynamics at barrier tissues and control of molting in Drosophila
(2017-04-19)
The insect epidermal cuticle acts as the exoskeleton and has crucial barrier functions, protecting against wounding, desiccation, invading pathogens and other environmental dangers. During the life of insects, the epidermal ......
The TsdA family of thiosulfate dehydrogenases/tetrathionate reductases
(2017-04-24)
TsdA enzymes are a phylogenetically widespread family of periplasmic c-type diheme cytochromes which catalyse both thiosulfate oxidation and tetrathionate reduction. The reaction directionality varies between enzymes ...
Medium-chain fatty acid metabolism in hepatocytes and adipocytes
(2017-04-11)
Fatty acids (FAs), in free form or incorporated into complex lipids, constitute an inseparable part of the daily human diet. Different carbon atom chain length and saturation rate leads to a huge variety of FAs of which ...
Physiological role of cation channels of P. irradians ciliary photoreceptors and human sperm
(2017-04-07)
Eukaryotic flagella and cilia are antenna-like cellular extrusions, shaped by microtubules and covered by a specialized extension of the plasma membrane. They serve several tasks, like light and olfactory sensation or cell ......
Eukariotische Flagellen und Zilien sind antennenartige Strukturen, die von Mikrotubuli durchzogen und von einer spezialisierten Erweiterung der Plasmamembran überzogen sind. Sie erfüllen verschiedenste physiologische Rollen, ......
Eukariotische Flagellen und Zilien sind antennenartige Strukturen, die von Mikrotubuli durchzogen und von einer spezialisierten Erweiterung der Plasmamembran überzogen sind. Sie erfüllen verschiedenste physiologische Rollen, ......
The Relationship between Astrocytes, Inflammation and Epileptogenesis
(2017-08-23)
Previous studies provided evidence that FSs in children increase the risk of epilepsy development. EFSs in animals confirmed this assumption. EFS generated with only hyperthermia induction caused astrocyte uncoupling, which ...