The Faculty of Mathematics and Natural Sciences: Search
Now showing items 1021-1030 of 1159
Animal-Robot Interactions: Electrocommunication, Sensory Ecology, and Group Dynamics in a Mormyrid Weakly Electric Fish
(2018-12-12)
Mormyrid weakly electric fish possess a specialized electrosensory system. During the process of active electrolocation, these animals perceive self-generated electric organ dis-charges (EOD) and are thereby able to detect ...
Patientenspezifische induziert pluripotente Stammzellen als Modellsystem zur Untersuchung der lysosomalen Speichererkrankung Metachromatische Leukodystrophie
(2019-02-14)
Die Metachromatische Leukodystrophie (MLD) wird verursacht durch eine funktionelle Defizienz des metabolischen Enzyms Arylsulfatase A (ARSA). Unter physiologischen Bedingungen baut ARSA das Membranlipid 3'-O-Sulfo-Galakt ......
Functional in vivo calcium imaging in the hippocampus under healthy and disease conditions
(2020-04-22)
The hippocampus has long been known to be essential for all features of memory processing. Hippocampal function strongly depends on the orchestrated activity of transiently autonomous neuronal populations that create the ......
The role of diacylglycerol acyltransferase 1 in hepatic medium-chain fatty acid metabolism
(2020-01-28)
Fatty acids form a class of important biomolecules, serving as essential elements of lipid molecules. Stored in triacylglycerol (TAG), the main constituent of plant oils and animal fats, they from an inseparable part of ......
Creld1 controls T cell homeostasis in mouse and human
(2020-07-07)
Cysteine-rich with EGF-like domains 1 (Creld1) was recently found to be fundamental for the VEGF-mediated activation of NFATc1 during heart development. Creld1 complete KO in mice is lethal due to developmental problems ...
Bridging between data and knowledge: New ways to better understand Alzheimer's Disease and Type 2 Diabetes comorbidity
(2021-06-15)
The holistic understanding of biological phenomena enabled by systems biology forms the basis of current research. As opposed to the principle of classical biology where behavior of a biological system is explained by ...
Odor-evoked modulation of the olfactory bulb by projections from the horizontal limb of the diagonal band of Broca
(2021-07-09)
Olfactory input encodes essential information about the environment and shapes adapted behavioral reactions. Hence, the olfactory system is complex with diverse brain areas processing the sensory input on different levels. ...
Radiometalle in der nuklearmedizinischen Anwendung: Prozessentwicklung und Translation in die klinische Routineanwendung
(2022-04-20)
In der vorliegenden Arbeit wurden mehrere Aspekte der täglichen radiopharmazeuti-schen Arbeit in der Nuklearmedizin bearbeitet. Der Fokus lag dabei auf der Translation von neuen Tracern aus der Forschung in die klinische ...
Interplay between the amyloid precursor protein (APP) and α-secretases at the plasma membrane
(2022-04-21)
Alzheimer’s disease (AD) is the most common form of dementia. A principle pathological feature of AD are senile plaques consisting of extracellular aggregations of amyloid β peptides (Aβ). Aβ is derived from the amyloid ...
Nemertean Systematics: Usefulness of DNA Barcoding and DNA Taxonomy for Species Identification, Delimitation, and Population Analyses
(2022-04-21)
The assessment of phylogenetic relationships and systematics of all metazoan taxa heavily relies on the accurate identification and delimitation of species. For the past two centuries, both species identification and ...