The Faculty of Mathematics and Natural Sciences: Mathematisch-Naturwissenschaftliche Fakultät: Recent submissions
Now showing items 301-320 of 4923
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Synthese neuer molekularer Abstandshalter zur Adsorption auf Festkörperoberflächen
(2024-11-11)Im Rahmen dieser Arbeit wurden neue definierte Makrozyklen (MZ) präsentiert, die durch ihre in drei lateralen Richtungen vororientierten Alkoxy-Seitenketten eine vorhersagbare Parkettierung der HOPG-Oberfläche an der ... -
Synthesis and chemistry of P-bridged, bent and planar bis(N-heterocyclic) carbenes
(2024-11-08)This PhD thesis focuses on the synthesis of new 7,8-dihydro-1,4-diphosphabarrelenes and their subsequent conversion into the corresponding P-bridged bis(imidazolium) salts and bis(N-heterocyclic) carbenes (bis(NHCs)).<br ... -
Untersuchungen zur heterologen Biosynthese des seltenen kompatiblen Soluts Nε-Acetyl-β-Lysin
(2024-11-07)Das Aminosäurederivat N<sub>ε</sub>-Acetyl-β-Lysin (NAβL) wird von methanogenen Archaeen und einigen Vertretern der Bakterien zur Anpassung an osmotischen Stress produziert. Bisher wurden vor allem die zur Produktion ... -
Role of the AhR-Repressor and AhR-dependent CYP1 Monooxygenases in Immune Cells Regulation
(2024-11-05)The Aryl hydrocarbon receptor (AhR) is a transcription factor that can be activated by various polyaromatic ligands and plays an important role in immune regulatory processes. AhR activity is regulated through the AhR-repressor ... -
Characterization of a PEM electrolyzer for ozone generation in ultrapure and drinking water applications
(2024-10-31)The electrolytic in situ generation of oxidants is an increasingly widespread technique for producing sanitized and thus safe process water in ultrapure water distribution systems. In particular, the anodic production of ... -
P and S-centred reactions in a thiazole-fused 1,4-diphosphinine: insights into addition and redox chemistry
(2024-10-31)Starting from a tricyclic, thiazole-2-thione-based 1,4-diphosphinine, the scope of both P- and S-functionalisations was explored. 1,4-addition reactions at the central ring were investigated, furnishing 1,4-dihydro-1,4-d ... -
Peptidomimetics in Drug Development: Substrates, Titrants, and Inhibitors to Study and Combat SARS-CoV-2 and Proteolysis Targeting Chimeras as 18F-Tracers
(2024-10-31)This thesis provides a profound contribution to the application spectrum of peptidomimetics in the drug discovery process. It demonstrates the exploration of the main protease (M<sup>pro</sup>) of SARS-CoV-2 through ... -
Sedimentological characterisation and provenance analysis of the pre-collisional Betic & Rif turbidite systems
(2024-10-30)(noch nicht zugänglich / not yet accessible) -
The Influence of Stellar Objects onto the Interstellar Medium: Isotopic Compositions and Maser Lines
(2024-10-30)This thesis investigates the influence of stellar objects onto the interstellar medium (ISM), following two lines of research, determining isotope ratios over much of the Milky Way and observing interstellar ammonia masers. ... -
Characterization and Operation of Final DEPFET Pixel Detector Modules for the Belle II Experiment
(2024-10-28)The Belle II experiment at the SuperKEKB super B-factory collects data from asymmetric-energy $e^+e^-$ collisions at the PUpsilonFourS resonance since 2019. Its goal is to collect a PB{}APB data set 50 times larger than ... -
Movements of Plant Organs: From Root Skototropism to Leaf Mimicking
(2024-10-24)Plants colonized land around 450 million years ago, facilitated by a symbiotic relationship with fungi, particularly through root-fungal co-evolution. This symbiosis was pivotal in developing complex root systems in modern ... -
Investigation of the Endothelial Protein C Pathway Response and its Influence on the Thrombotic Risk in Carriers of the Factor V Leiden Mutation
(2024-10-22)Venous thrombosis and its potentially life-threatening complication pulmonary embolism are caused by the formation of an intravascular blood clot. Though there is a myriad of potential etiologies for this condition, the ... -
Mechanistic Investigations on Bacterial Enzymes from Sulfur Metabolism and Terpene Biosynthesis
(2024-10-21)This cumulative doctoral thesis encompasses six research articles focused on mechanistic investigations of sulfur metabolism and terpene biosynthesis. The primary focus of this research is on enzymes involved in the ... -
Nanoskalige, π-konjugierte Leiterpolymere
(2024-10-17)Im Rahmen der Dissertation wurden nanoskalige, π-konjugierte Leiteroligomere mit unterschiedlichen Abständen zwischen den Längsstreben synthetisiert. Die Kontrolle der Struktur und Konformation von Chromophoren in Polymeren ... -
Application of Machine Learning to Supersymmetric Models at Collider Experiments
(2024-10-16)In this thesis, we study the application of modern machine learning methods to searches for supersymmetric models of physics beyond the Standard Model. <br /> In recent years, resonant anomaly detection methods, such as ... -
Characterization and Optimization of Spray Freeze Drying Processes
(2024-10-14)(noch nicht zugänglich / not yet accessible) -
Mapping spiking network simulations to mathematically tractable rate models
(2024-10-14)Biological neural systems give rise to complex cognitive functions by processing information through interactions between neurons in the form of discrete spikes. While neuroscientists have developed a solid understanding ... -
Investigation of the interactions between analytes and stationary phases in gas chromatographic systems using simulation
(2024-10-11)Volatile compounds are responsible for the odour of food, characterize their authenticity or potential health risks. One technique for investigating volatile compounds is gas chromatography. The method development is often ... -
Context-aware Human Motion Anticipation
(2024-10-11)This thesis addresses the challenges of human motion anticipation and evaluation in complex contexts such as social interactions and human intention, focusing on motions lasting beyond one second. Central to our approach ... -
Untersuchungen zur Hemmung der Ectonucleotidase NPP1 auf Tumorzellen durch Heparinderivate und deren Konsequenzen für eine Deregulierung der antitumoralen Immunreaktion
(2024-10-11)Die ubiquitär exprimierte Enzymklasse der Ektonukleotidasen (EN) reguliert die purinerge Signaltransduktion über die Purinderivate Adenosin und ATP. Dabei erfolgt die Darstellung von Adenosin aus ATP unter anderem durch ...
