The Faculty of Mathematics and Natural Sciences: Mathematisch-Naturwissenschaftliche Fakultät: Recent submissions
Now showing items 301-320 of 4988
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Environmentally induced development of pulmonary monocyte-derived alveolar macrophages is controlled by Apolipoprotein E and Dectin-1
(2025-03-06)The lung is one of the largest barrier tissues of our body, and is constantly exposed to the environment. By inhaling, the lungs do not only take up oxygen, which is crucial for cellular respiration, but also a plethora ... -
Investigating Graphene-Based Systems: Interaction Effects, Localization, and Finite-Temperature Dynamics
(2025-03-05)This dissertation presents a comprehensive theoretical and numerical investigation into the electronic properties of graphene‐based systems, with a focus on interaction effects, localization phenomena, and finite‐temperature ... -
Ultracold fermions in periodically-driven superlattices
(2025-03-05)This thesis presents quantum simulation of strongly-correlated systems beyond standard Hubbard models, using ultracold fermionic potassium atoms in both static and periodically-driven optical superlattices. For this study, ... -
Efficient Prediction of Mole Fraction Related Vibrational Frequency Shifts
(2023-11-16)While so far it has been possible to calculate vibrational spectra of mixtures at a particular composition, we present here a novel cluster approach for a fast and robust calculation of mole fraction dependent infrared and ... -
A Quantum Cluster Equilibrium Theory for Multi-Component Liquids
(2024-02-19)In this work, we present a new theory to treat multi-component liquids based on quantum-chemically calculated clusters. The starting point is the binary quantum cluster equilibrium theory that is able to treat binary ... -
Adaptive Geospatial Data Representation for Data Analytics and Sharing in the Mobility Domain
(2025-02-25)In recent years, the mobility domain has gained attention from urban planners and researchers due to its essential role in enhancing urban safety and development. This interest can be attributed to the increased availability ... -
Development of the first geldanamycin-based HSP90 degraders
(2023-06-28)Despite the early clinical promise, adverse events such as acquired resistance and dose-limiting toxicities have barred the widespread use of HSP90 inhibitors as anticancer drugs. A new approach involving proteolysis-targeting ... -
A Systematic Database Approach to Identify Companion Diagnostic Testing in Clinical Trials under the New In Vitro Diagnostic Medical Devices Regulation
(2023-06-12)The European Union In Vitro Diagnostic Medical Devices Regulation (EU) 2017/746 (IVDR) introduces companion diagnostics (CDx) as a new legal term. CDx are applied in combination with a medicinal product to identify patient ... -
Quantum optimal transport for AF-C*-algebras
(2025-02-14)We introduce quantum optimal transport of states on tracial AF-C*-algebras to study non-spatial transport of quantum information, and view it as the pointwise case of a general parametrised one. We define quantum optimal ... -
A Cell Panel to Characterise Tau Aggregation
(2025-02-13)Tauopathies are neurodegenerative diseases characterised by the pathological folding of Tau into highly ordered, β-sheet rich fibrils (so-called amyloid), which progressively spread through the central nervous system in a ... -
Betrachtung des Zellmetabolismus mit Fokus auf Hexokinase 2 und IGFBP-2 im Tumorresistenzgeschehen
(2025-02-11)Bei der Behandlung solider Tumore mit Zytostatika ist oft eine Resistenzentwicklung zu verzeichnen, die ein Therapieversagen verursachen kann. Es ist bekannt, dass Tumorzellen oft einen veränderten Stoffwechsel besitzen. ... -
Analysis of the cAMP-regulated metabolome of skeletal muscle and adipose tissue
(2025-02-10)Aging, obesity and physical inactivity are three major risk factors leading to non-communicable diseases, like coronary heart disease or type 2 diabetes, resulting in reduced health and quality of life. As the number of ... -
The essential role of Cytohesin-2 as a regulator of intracellular transport
(2025-02-06)The protein family of cytohesins, comprising cytohesin-1 to -4, was identified between 1996 and 2000 as small guanine nucleotide exchange factors for ADP ribosylation factor (ARF) GTPases. Since then, the function of ... -
Boundary conditions and dynamics of fluvial obstacle mark formation
(2025-02-05)Obstacles like boulders, riparian vegetation, and man-made structures such as bridge piers are common in fluvial environments. When exposed to flow, they form characteristic geomorphological and sedimentary structures known ... -
Spatial Priors and Uncertainty for Enhanced Reconstruction in Computer Graphics and Vision
(2025-02-04)Many tasks in computer vision aim to reconstruct unknown quantities from observations of a scene, such as estimating depth from stereo vision, generating intermediate video frames, or revealing hidden shapes from transient ... -
Operationalizing Empathic and Supportive Communication in Natural Language Processing
(2025-02-04)Empathic communication is a significant aspect of support and health-oriented interactions. Theoretical models for clinical and counseling conversations outline its role in fostering open disclosure between patients and ... -
Towards High Precision Measurements of Higgs Boson Properties in the Di-Tau Decay with the ATLAS Detector
(2025-01-28)The Standard Model of particle physics (SM) describes the known fundamental particles and their interactions. The model is found to be incomplete with a need for extensions in order to cover all current experimental ... -
Cross-Lingual Ontology Matching and Enrichment
(2025-01-28)The Semantic Web has emerged as a foundational paradigm for representing and interlinking data in a semantically meaningful manner. Central to this paradigm are ontologies, pivotal for encapsulating spatial knowledge and ... -
Hordeum erectifolium, a physiological and genomic study of drought-adaptive traits
(2025-01-24)Drought stresses plants at multiple levels, affecting water uptake, stomatal evaporation, and intracellular stability, which in turn impacts plant fitness and yield. To develop climate-resilient crops, I investigated ... -
Compact Description for High Resolution Spatial Weather Extremes
(2025-01-22)Detecting local climate change signals, particularly within the context of extreme weather events, is challenging due to the significant internal variability of the climate system. This thesis, part of the BMBF-funded ...
