The Faculty of Mathematics and Natural Sciences: Mathematisch-Naturwissenschaftliche Fakultät: Recent submissions
Now showing items 581-600 of 4994
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Purely time-dependent optimal control of quasilinear parabolic PDEs with sparsity enforcing penalization
(2022-01)We prove first- and second-order optimality conditions for sparse, purely time-dependent optimal control problems governed by a quasilinear parabolic PDE. In particular, we analyze sparsity patterns of the optimal controls ... -
Sparse optimal control of a quasilinear elliptic PDE in measure spaces
(2022-03)We prove existence of optimal controls for sparse optimal control of a quasilinear elliptic equation in measure spaces and derive first-order necessary optimality conditions. Under additional assumptions also second-order ... -
Low-rank approximation of continuous functions in Sobolev spaces with dominating mixed smoothness
(2022-03)Let Ω<sub><em>i</em></sub> ⊂ R<em><sup>n<sub>i</sub></sup></em> , <em>i</em> = 1, . . . , <em>m</em>, be given domains. In this article, we study the low-rank approximation with respect to L<sup>2</sup>(Ω<sub>1</sub> × · ... -
In-situ Estimation of Time-averaging Uncertainties in Turbulent Flow Simulations
(2022)The statistics obtained from turbulent flow simulations are generally uncertain due to finite time averaging. The techniques available in the literature to accurately estimate these uncertainties typically only work in an ... -
A dimension-adaptive combination technique for uncertainty quantification
(2022-04)We present an adaptive algorithm for the computation of quantities of interest involving the solution of a stochastic elliptic PDE where the diffusion coefficient is parametrized by means of a Karhunen-Loève expansion. The ... -
A note on source term representation for control-and-state-constrained parabolic control problems with purely time-dependent control
(2022-06)We revisit the concept of source term representation, originally developed for boundary control problems subject to pointwise state constraints in the domain, and apply it to linear-quadratic parabolic control problems ... -
Knowledge discovery assistants for crash simulations with graph algorithms and energy absorption features
(2022)We propose the representation of data from finite element car crash simulations in a graph database to empower analysis approaches. The industrial perspective of this work is to narrow the gap between the uptake of modern ... -
Sedimentology and geochemistry of the Jurassic system in northern Iraq: Implications for paleoenvironmental reconstruction, provenance and tectonic setting
(2024-08-06)This cumulative thesis presents pioneering studies on the paleoclimate, paleosalinity and paleoredox conditions, prevailing during the Jurassic period in northern Iraq, based on a variety of proxies. To this end, several ... -
Lipidic cubic phase crystallization of the adenosine A2B receptor in complex with antagonists
(2024-07-29)G protein-coupled receptors (GPCRs) are membrane-bound signaling proteins that are fundamental to human life. Through their signal transduction, they can affect virtually all aspects of human physiology and are consequently ... -
Investigation of the lysosomal proteome in neuronal ceroid lipofuscinosis caused by CLN6 deficiency and interactome studies to identify novel interaction partners of CLN6
(2024-07-29)Neuronal ceroid lipofuscinoses (NCLs) account for the majority of genetic neurodegenerative diseases in infancy. However, for most forms of this serious disease there is no adequate treatment available. In the NCL6 subtype, ... -
Dispersively improved vector-meson-dominance approaches to precision observables
(2024-07-29)To this day, describing the interaction of hadrons poses a challenge. Although quantum chromodynamics is well established by now, its non-perturbative nature at low energies renders it impossible to perform perturbative ... -
Investigating multiple stressor effects at the molecular level: Transcriptomic profiling of freshwater macroinvertebrate species exposed to anthropogenic stressors
(2024-07-29)Freshwater ecosystems are simultaneously exposed to multiple anthropogenic stressors, resulting in a global decline of freshwater biodiversity. Identifying the drivers of stream ecosystem deterioration is challenging because ... -
Japan 1873-1875: Die Tagebücher des Bonner Geographieprofessors Johannes Justus Rein ; Band 2
(2021)Nach der Publikation des ersten Bandes im 2020 werden in diesem zweiten Band die verbliebenen beiden Tagebbuchbände von Lehrstuhlinhabers für Geographie an Bonner Universität Johannes Justus Rein (1835-1918) vorgelegt. ... -
Japan 1873-1875: Die Tagebücher des Bonner Geographieprofessors Johannes Justus Rein ; Band 1
(2020)In diesem Buch werden die ersten beiden Bände der Tagebücher von Lehrstuhlinhabers für Geographie an Bonner Universität Johannes Justus Rein (1835-1918) in heute lesbarer Schrift vorgelegt. <br> Die Edition der Tagebücher ... -
Two-pion exchange contributions for coupled-channel B(*)B(*) and B(*) B(*) scattering
(2024-07-26)In the paper [Phys.Rev.D 99 (2019) 9, 094013] of V. Baru et al., the LO and incomplete NLO potentials were utilised to investigate the line shapes of Zb(10610) and Zb(10650) and their (yet to be discovered) spin partners. ... -
Oster-Insel und Brodbaum: Meilensteine im geographischen Denken von Georg Forster (1754-1794)
(2019)Die vorliegende Arbeit fragt anhand zweier Beispiele nach Forsters Beitrag für die Konstituierung geographischen Denkens in der Phase der Präklassischen Geographie (1750 – 1798) vor der Institutionalisierung ... -
Sperm Guidance in Zebrafish
(2024-07-24)The core challenge of the fertilization process is one of pathfinding: how do motile sperm cells locate the immotile oocyte? In some species, this process is well studied, e.g. sea urchin and human. Both species employ ... -
Investigation and Development of Quantum Chemical Solvation Models
(2024-07-24)The main topic of this thesis is the investigation and development of quantum chemical solvation models. In combination with modern quantum chemical methods, these models can predict various molecular properties for complex ... -
Tests of lepton universality in the rates of inclusive semileptonic B-meson decays at Belle II
(2024-07-23)This thesis presents two precision tests of lepton universality: the first measurement of the ratio of light-lepton branching fractions of inclusive semileptonic <em>B</em>-meson decays, <em>R(X<sub>e/μ</sub>) = ℬ(B ... -
A story about difluoromethyl-1,3,4-oxadiazoles: Synthesis and biochemical evaluation of an enigmatic novel zinc binding group for the highly selective inhibition and degradation of histone deacetylase 6
(2024-07-22)Histone deacetylase 6 (HDAC6) is a valuable pharmaceutical target in oncological and non-oncological diseases. Classical selective HDAC6 inhibitors utilize a hydroxamic acid as zinc binding group (ZBG), which is associated ...
