Mathematisch-Naturwissenschaftliche Fakultät: Mathematisch-Naturwissenschaftliche Fakultät: Neuzugänge
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A census on the gas content of star-forming galaxies over the past 11 billion years of the universe
(2024-07-17)With the advent of the Atacama Large Millimeter/submillimeter Array (ALMA), we now have the opportunity to measure the physical properties of the cold, dense, star-forming interstellar medium (ISM) even in distant, ... -
The elucidation of the modes of action of moenomycin and corallorazine A
(2024-07-16)Antimicrobial resistance poses a serious threat to public health worldwide. To overcome this global problem and ensure the supply of effective antibiotics for the therapy of infectious diseases in the future requires to ... -
Synthesis and Characterization of Histone Deacetylase (HDAC) Inhibitors and PROTACs
(2024-07-11)Histone deacetylases (HDACs) are a class of enzymes that remove acyl groups from ε-N-lysine residues of histone and non histone proteins. There are 18 human HDAC isoforms, of which 11 have a Zn2<sup>+</sup> ion in their ... -
PDE-based Lossless Medical Image Compression
(2024-07-09)In this dissertation, our scientific goal is to investigate the potential of Partial Differential Equations (PDEs) for designing a lossless medical image compression codec. <br /> The dissertation consists mainly of ... -
Effects of habitat fragmentation on herpetofauna in Southeast Asia: From broad scale responses to fine scale responses in an ever-changing anthropogenic landscape
(2024-07-05)Habitat loss and fragmentation are undoubtedly significant drivers of biodiversity loss worldwide, with Southeast Asia being a hotspot of biodiversity and facing numerous anthropogenic pressures. However, the impacts of ... -
Katalysatoren für die thermische Sauerstoffentwicklungsreaktion
(2024-07-05)Ziel dieser Arbeit ist es ein geeignetes Anodenmaterial für die PCEC (Protonenkeramikelektrolyse) anhand theoretischer Rechnungen vorauszusagen, welches ausschließlich umweltfreundliche, häufige und kostengünstig verfügbare ... -
Microscopic Theory of Photon Bose-Einstein Condensation
(2024-07-05)We introduce a novel approach for analysing light-matter interactions within driven-dissipative environments. Our study centers on the interaction between dye molecule solutions and photonic cavity modes, mediated by ... -
From the stellar IMF to large-scale structure formation: How the ΛCDM model is incompatible with observations over all probed astrophysical scales
(2024-07-05)This doctoral thesis investigates the current standard model of cosmology (Λ Cold Dark Matter – ΛCDM – framework) by performing tests on different astrophysical scales which could indicate if the missing mass ... -
Identifizierung und Vermeidung von Medikationsfehlern in der Tumortherapie
(2024-07-05)Medikationsfehler in der Tumortherapie können fatale Auswirkungen haben. Die kontinuierliche Verbesserung des Medikationsprozesses sowie die Erhöhung der Arzneimitteltherapiesicherheit sind daher von entscheidender Bedeutung. ... -
Establishing SNPSTR Markers to Fight Illegal Wildlife Trade
(2024-07-04)One of the causes of the loss of biodiversity on this planet is the over-exploitation by humans. Even though laws and policies are in place for the protection of endangered species, illegal wildlife trade remains an ... -
Dissecting the cellular effects of antimicrobial agents: The spatio-temporal impact of peptidoglycan synthesis inhibiting antibiotics in Staphylococcus aureus and mechanism of action elucidation of epilancin A37
(2024-07-03)The increasing threat of antibiotic resistance requires innovation in antibiotic research and development. However, the knowledge of how antimicrobial agents kill bacteria is still limited, even for clinically relevant ... -
Developing computational protocols for molecular spectroscopy that are able to unravel the photophysical properties of photoluminescent inorganic solid state and organometallic materials
(2024-07-02)The aim of the thesis is to conduct a thorough examination of photoluminescent inorganic solid-state and organometallic materials through comprehensive theoretical and computational analyses. This involves unraveling the ... -
The redshift evolution of galactic-scale magnetic fields
(2024-06-27)Magnetic fields play an important role in galaxy evolution, however, the redshift evolution of galactic-scale magnetic fields is not well constrained, with only a handful of direct magnetic field strength measurements in ... -
Formulation Development and Optimization via In Vivo Predictive In Vitro and In Silico Tools
(2024-06-25)Corallopyronin A (CorA) is a natural anti-infective compound which is able to deplete Wolbachia, endosymbionts of the filarial nematodes. Challenging physicochemical properties of the neat drug (low aqueous solubility, ... -
Identification of molecular mechanisms that may contribute to the antidepressant effect of St. John's wort extract Ze 117
(2024-06-25)Chronic stress is one of the factors that contribute to the development and maintenance of depression. Previous studies have shown that the treatment of cultured cells with the natural stress hormone cortisol, but also ... -
On discrete Morse theory in persistent topology
(2024-06-25)The main topic of this thesis is the interplay between discrete Morse theory and persistent topology: we apply methods from discrete Morse theory to filtered complexes, as they appear in Topological Data Analysis, and study ... -
Kondo Collapse and Revival by Pulsed Light
(2024-06-24)The search and characterisation of new quantum phases of matter has recently been intensified by the application of terahertz (THz) spectroscopy in the time domain to heavy-fermion systems. It was experimentally shown that ... -
Modulation of filamin C interactions and function by mechanical stress-induced phosphorylations
(2024-06-24)When contracting, muscle cells are constantly exposed to mechanical stress with the resulting forces not only provoking unfolding and denaturation of proteins but also triggering cellular signaling processes, frequently ... -
Deep Representation Learning for Analyzing Financial and Cybersecurity Data
(2024-06-19)Recent years have shown a surge in the capability of deep learning models for various domains of interest and different types of data. Machine learning models are now capable of understanding, categorizing and generating ... -
Higgs Mode and Critical Temperature in the BCS-BEC Crossover
(2024-06-19)For this thesis, analogue quantum simulations of the BCS-BEC crossover have been performed. To this end, an ultracold gas of fermionic <sup>6</sup>Li atoms was prepared in an optical dipole trap. The gas is in a balanced ...
