Mathematisch-Naturwissenschaftliche Fakultät: Mathematisch-Naturwissenschaftliche Fakultät: Neuzugänge
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Using Advanced Machine Learning Techniques to Study Poorly Modeled Processes in pp Collisions with the ATLAS Detector
(2023-07-12)In high energy particle physics, measurements are made to improve and test our models. Some processes are difficult or impossible to model with current capabilities. For some, this means that one would estimate such processes ... -
Elucidation of multinumerous centrosomes and their impact on migration in dendritic cells
(2023)Centrosomes act as major microtubule organizing center (MTOC) in most animal cells and are well known for their role in building up the mitotic spindle during cell division. Core structure of the centrosome are two tubulus ... -
Physically Based Modeling of Micro-Appearance
(2023-07-11)This dissertation addresses the challenges of creating photorealistic images by focusing on generating and rendering microscale details and irregularities, because a lack of such imperfections is usually the key aspect of ... -
NHC-supported Disilavinylidenes and Oxysilylenes: Synthesis, Characterization and Reactivity Studies
(2023-07-06)Vinylidenes (:C=CR2) are a transient subclass of carbenes and readily isomerize to the respective alkynes (R C≡C R). While stabilization by metal coordination is possible, their instability is commonly utilized in the Corey ... -
Plant-type RNA editing transferred into Escherichia coli: Expected and surprising new insights for editing factors and how they recognize their targets
(2023-07-06)Plant-type C-to-U RNA editing is a post-transcriptional process that converts cytidines to uridines in mitochondrial and chloroplast transcripts. This process is mediated by pentatricopeptide repeat (PPR) proteins, which ... -
Effects of drought and the role of auxin on barley stamen maturation
(2023-07-04)Drought is a major abiotic stress that reduces crop yields all over the world. Climate change is predicted to increase the frequency and intensity of future drought events. Concomitantly, the increasing world population ... -
Hybrid Pixel Readout Chip Verification, Characterization and Wafer Level Testing for the ATLAS-ITK Upgrade at the HL-LHC
(2023-07-04)The HL-LHC upgrade starting in 2026 will provide an opportunity for new high-energy physics experiments, but also present challenges for its tracking detectors, particularly the pixel detectors close to the interaction ... -
Understanding the systemic immune response in COVID-19 – one cell at a time
(2023-07-03)This thesis comprises four self-contained essays on mechanism design without transfers. Chapters 1 and 2 characterize ex post and posterior implementation in collective decision problems with interdependent values. Chapters ... -
Deciphering the function of GCNF in human neural stem cells during neuronal differentiation
(2023-06-29)The human brain is one of the most complex structures described in the biological world and the development of such an intricate organ is tightly regulated by neural stem cell (NSC) proliferation and differentiation. ... -
Computational studies on δ-branch G protein-coupled P2Y and related orphan receptors
(2023-06-26)G protein-coupled receptors (GPCRs) represent an attractive target for drug development as the modulation of their activity can induce a desired physiological response to treat pathological conditions. Given the knowledge ... -
Details of the immune response and impact of the microbiome in murine calcific aortic valve stenosis
(2023-06-26)Calcific aortic valve stenosis (AVS) is the most common heart valve disorder in Western countries. It results from complex cellular processes involving valvular interstitial, endothelial and immune cells, which lead to ... -
Climate and land use change impacts on floods in the Mono River basin of Togo and Benin
(2023-06-22)Floods are prominent in West Africa and are expected to exacerbate due to global changes, including climate change, land use change, as well as industrial and infrastructure development. It is important to evaluate in ... -
Role of the proton channel HVCN1 in the regulation of neutrophil activation
(2023-06-22)Excessive neutrophil activation is a feature of many inflammatory diseases. Neutrophils from affected patients are prone to release reactive oxygen species (ROS) and toxic granule proteins or to undergo NETosis, a special ... -
Untersuchungen zur Wirkungsweise von Cervimycin
(2023-06-22)Durch die Zunahme von Antibiotika-Resistenzen werden neue antimikrobiell wirksame Substanzen dringend gebraucht, laut WHO unter anderem gegen Staphylococcus aureus. Diese Arbeit gliedert sich in zwei Teile, zum einen die ... -
Suspension Feeders as Biological Models to Develop Biomimetic Filter Modules and Reduce Microplastic Emissions
(2023-06-22)With every wash cycle, microplastic fibres are released from textiles and enter the environment via the wastewater system. In order to develop an innovative washing machine filter, a biomimetic approach was employed. In ... -
Molecular determinants of prostate cancer aggressiveness: an analysis of the interconnection between biomarkers,disease drivers and resistance mechanisms towardsnovel diagnostic, theranostic and therapeutic approaches
(2023-06-21)The diagnosis of prostate cancer (PCa) is still mainly based on morphological criteria but is supported by biomarker analysis, which is currently mainly performed on an immunohistochemical basis. Newly developed techniques ... -
Biosynthesis and Analysis of 3-Isobutyl-2-methoxypyrazine in Capsicum annuum (Bell Pepper) Plants
(2023-06-21)3-Alkyl-2-methoxypyrazines (MPs) are highly odorous compounds occurring in a wide range of raw vegetables. Due to their high odor activity, they have been of great research interest. The most prominent MPs are 3-isopropy ... -
Identification of cisplatin resistance mechanisms and alternative treatment options for testicular germ cell tumors
(2023-06-21)Type II testicular germ cell tumors (TGCTs) are the most prevalent tumors in young men aged 18 to 35 years. TGCTs are classified as seminomas and non-seminomas. Embryonal carcinomas (EC), representing the cancer stem cell ... -
Contesting Rural Futures: Political and Agrarian Change in Tanzania's Kilombero Valley during the Presidency of John P. Magufuli (2015 - 2021)
(2023-06-19)The Arusha Declaration, written by the state founder Julius Nyerere in 1967, was replaced around the year 2000 by a new national development vision, Vision 2025. State visions of the future of the nation on the one hand ... -
Investigating pathomechanisms underlying malformations of human cortical development
(2023-06-15)During human development the brain has to form a complex neuronal network requiring a well-orchestrated sequence of neurogenesis, neuronal migration and correct positioning within cortical layers followed by synaptogenesis. ...
