Mathematisch-Naturwissenschaftliche Fakultät: Mathematisch-Naturwissenschaftliche Fakultät: Neuzugänge
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Numerical Approximation of Optimal Microstructures in Elastic Shape Optimization
(2023-06-15)We develop and analyze a numerical two-scale optimization scheme for structural shape optimization. Whenever cost functionals, such as the elastic energy, are subject to minimization, while meeting a constraint on the ... -
Analysis of the MBO scheme: from materials science to data clustering
(2023-06-15)The Merriman, Bence, and Osher (MBO) scheme -- also known as thresholding scheme -- is a numerical method originally introduced to approximate the evolution by mean curvature flow (MCF). The algorithm produces a time ... -
Automatic Evaluation of Dialogue-Systems Using Neural-Network Methods
(2023-06-05)We usually interact with computers by means of specialized tools that are not as common as the language humans use. This has motivated researchers for already several decades to develop algorithms that enable interfacing ... -
Baryon properties from chiral QCD
(2023-06-05)This thesis contains a collection of studies on the properties of baryons within the context of effective field theory, especially Chiral Perturbation Theory. The thesis focuses primarily on the Roper resonance, an excited ... -
Untersuchung der molekularen Mechanismen einer Thrombozytenaktivierung durch Karzinomzellen und die Rolle des Tumormarkers MACC1 in diesem Prozess
(2023-05-31)Die Interaktion der Tumorzellen mit Thrombozyten und die damit einhergehende Aktivierung ist ein Schlüsselfaktor der Tumormetastasierung. Die molekularen Mechanismen einer Thrombozytenaktivierung durch Tumore können sehr ... -
Glial dysfunction in the pathology of temporal lobe epilepsy
(2023-05-30)Epilepsy is a common neurological disorder characterized by periods of transient abnormal electrical brain activity, which manifests as behavioral symptoms known as epileptic seizures. Despite intense research, the underlying ... -
Assays and ligands for underexplored membrane proteins with potential as future drug targets
(2023-05-30)In this study, pharmacological assays were established and employed to identify and characterize compounds regarding their potential as tool compounds, lead structures, and drug candidates for three underexplored potential ... -
Morphological evolution and phylogeny of millipedes (Diplopoda)
(2023-05-25)Millipedes (Diplopoda) count more than 12,000 described species and play, probably since more than 400 million years, a fundamental role as detritivores in terrestrial ecosystems. Despite their great diversity and ecological ... -
Studien zur Untersuchung der Interaktion von Häm und Hämopexin
(2023-05-24)In hämolytischen Zuständen lysieren Erythrocyten, es tritt Hämoglobin aus und dieses setzt Häm frei. Das Eisenion von Häm kann an Fenton-artigen Reaktionen teilnehmen, die reaktive Sauerstoffspezies produzieren. Diese ... -
Gravity Tests with Pulsars Using New-Generation Radio Telescopes
(2023-05-23)Pulsar timing is a powerful tool for studying a wide range of questions in fundamental physics, including the equation of state (EOS) of super-dense matter, tests of general relativity (GR) and alternative theories of ... -
Internally Contracted Multireference Coupled-Cluster Theories With Automated Code Generation
(2023-05-22)Developing a coupled-cluster theory based on a multiconfigurational reference wave function still is one of the most challenging problems in quantum chemistry, both from a theoretical and implementational perspective. ... -
On growth patterns and mechanisms in Mediterranean-alpine shrubs
(2023-05-22)In the context of open questions on the adaptability of alpine ecosystems to future global warming, this cumulative doctoral dissertation studies three Mediterranean-alpine shrub species using a novel dendrometer-based ... -
Optimisation of the Data Reduction for the Belle II Pixel Detector and Development of a new Track Finding Algorithm using the Belle II Vertex Detector
(2023-05-15)The Belle II experiment, located at the SuperKEKB collider in Tsukuba, Japan, is recording data at world record luminosities in order to provide world-leading results in the field of particle physics in the future. To ... -
Self-Supervised Video Representation Learning and Downstream Applications
(2023-05-12)Video understanding is an important computer vision task with a great variety of different applications, such as autonomous driving, robotics and video surveillance. Much progress has recently been made on video understanding ... -
Cellular mechanoresponse to extracellular matrix shear strain and stiffness studied in a cell culture model of breast gland development
(2023-05-12)Mechanobiological regulation is a crucial element for tissue development and homeostasis. Dysregulation of the normal mechanobiological microenvironment of cells is linked to disease and negatively affects cancer patients' ... -
GLOSTAR: Investigating Tracers of Early High-Mass Star Formation
(2023-05-12)High-mass stars (>8 msol) are not as numerous as their less massive counterparts but have a much more profound impact on their environment within their native galaxies. Despite their importance, our understanding of their ... -
Infinitesimal analysis of singular stochastic partial differential equations
(2023-05-10)The last decade has seen a considerable rise in the study of singular stochastic partial differential equations (SPDEs) which turned into the birth of many celebrated techniques for the development of a solution theory for ... -
Mechanistic investigations of organocatalytic and gold-catalyzed reactions and synthetic approach towards a chiral bifunctional catalyst
(2023-05-09)The first part of this thesis focuses on the mechanistic studies of an intermolecular cyclization reaction between an α,β-unsaturated aldehyde and an electron deficient primary alkyne to a cyclopentene carbaldehyde. Based ... -
Access to and reactions of P-functional tetrathiafulvalene derivatives
(2023-05-09)This Ph.D. thesis describes the chemistry of the first P-functional tetrathiafulvalenes; the chlorophosphanyl-substituted TTFs were subjected to a reaction with Galliumtrichloride, as a chloride abstraction reagent, to ... -
Functions and regulation of synaptopodin-2 isoforms under mechanical stress in muscle cells
(2023-05-09)Synpo2 isoforms are adapter proteins in myofibrillar Z-disc of striated muscle engaged in the homeostasis of the actin-crosslinking protein filamin C under mechanical stress. They interact with the co-chaperone BAG3, which ...
