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Anzeige der Dokumente 18-21 von 21
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Second-line and third-line therapy with nanoliposomal irinotecan (nal-IRI) in pancreatic cancer: a single-center experience and review of literature
Möhring, Christian; Frontado Graffe, Freddy José; Bartels, Alexandra; Sadeghlar, Farsaneh; Zhou, Taotao; Mahn, Robert; Marinova, Milka; Feldmann, Georg; Brossart, Peter; Glowka, Tim; Kalff, Jörg; Strassburg, Christian; Gonzalez-Carmona, Maria (2023-02-15)Background: Prognosis of patients with pancreatic cancer is still extremely poor. First-line palliative therapies with FOLFIRINOX or gemcitabine/nab-paclitaxel have been established in the last decade. In the second-line, ... -
Sympathetic Innervation Modulates Mucosal Immune Homeostasis and Epithelial Host Defense
Mallesh, Shilpashree; Ten Hove, Anne S.; Schneider, Reiner; Schneiker, Bianca; Efferz, Patrik; Kalff, Jörg C.; de Jonge, Wouter J.; Wehner, Sven (2022-08-21)Intestinal mucosal cells, such as resident macrophages and epithelial cells, express adrenergic receptors and are receptive to norepinephrine, the primary neurotransmitter of the sympathetic nervous system (SNS). It has ... -
UDP-glucuronosyltransferase polymorphisms affect diethylnitrosamine-induced carcinogenesis in humanized transgenic mice
Landerer, Steffen; Kalthoff, Sandra; Paulusch, Stefan; Strassburg, Christian P. (2020-08-28)UDP-glucuronosyltransferase (UGT) 1A enzymes detoxify a broad array of exogenous compounds including environmental toxins and carcinogens. Case-control studies identified genetic variations in UGT1A genes leading to reduced ... -
Virtual reality in the diagnostic and therapy for mental disorders: A systematic review
Wiebe, Annika; Kannen, Kyra; Selaskowski, Benjamin; Mehren, Aylin; Thöne, Ann-Kathrin; Pramme, Lisa; Blumenthal, Nike; Li, Mengtong; Asché, Laura; Jonas, Stephan; Bey, Katharina; Schulze, Marcel; Steffens, Maria; Pensel, Max Christian; Guth, Matthias; Rohlfsen, Felicia; Ekhlas, Mogda; Lügering, Helena; Fileccia, Helena; Pakos, Julian; Lux, Silke; Philipsen, Alexandra; Braun, Niclas (2022-10-30)Background: Virtual reality (VR) technologies are playing an increasingly important role in the diagnostics and treatment of mental disorders. Objective: To systematically review the current evidence regarding the use ...