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Bidirectional Effect of Long-Term Δ⁹‑Tetrahydrocannabinol Treatment on mTOR Activity and Metabolome

Bilkei-Gorzo, Andras; Schurmann, Britta; Schneider, Marion; Kraemer, Michael; Nidadavolu, Prakash; Beins, Eva C.; Müller, Christa E.; Dvir-Ginzberg, Mona; Zimmer, Andreas (2024-08-14)

Brain aging is associated with cognitive decline, reduced synaptic plasticity, and altered metabolism. The activity of mechanistic target of rapamycin (mTOR) has a major impact on aging by regulating cellular metabolism. ...