How to control cyclic nucleotide signaling by light
How to control cyclic nucleotide signaling by light
View/Date of Publication
10.03.2017Publisher
AmsterdamPublisher Location
Elsevier ScienceMetadata
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Citable Link (Handle URI) 
https://hdl.handle.net/20.500.11811/9772
Abstract
Optogenetics allows to non-invasively manipulate cellular functions with spatio-temporal precision by combining genetic engineering with the control of protein function by light. Since the discovery of channelrhodopsin has pioneered the field, the optogenetic toolkit has been ever expanding and allows now not only to control neuronal activity by light, but rather a multitude of other cellular functions. One important application that has been established in recent years is the light-dependent control of second messenger signaling. The optogenetic toolkit now allows to control cyclic nucleotide-dependent signaling by light in vitro and in vivo.
Subjects
cyclic nucleotides, optogenetics
Classification (DDC)
570 Biowissenschaften, Biologie 610 Medizin, GesundheitPublished in
Current Opinion in Biotechnology, 2017, 48, pp. 15-20First Publication
https://doi.org/10.1016/j.copbio.2017.02.014Jansen, Vera; Jikeli, Jan F.; Wachten, Dagmar: How to control cyclic nucleotide signaling by light. In: Current Opinion in Biotechnology. 2017, 48, 15-20.
Online-Ausgabe in bonndoc: https://hdl.handle.net/20.500.11811/9772
Online-Ausgabe in bonndoc: https://hdl.handle.net/20.500.11811/9772
@article{handle:20.500.11811/9772,
author = {{Vera Jansen} and {Jan F. Jikeli} and {Dagmar Wachten}},
title = {How to control cyclic nucleotide signaling by light},
publisher = {Amsterdam},
year = 2017,
month = mar,
journal = {Current Opinion in Biotechnology},
volume = 2017, 48,
pages = 15--20,
note = {Optogenetics allows to non-invasively manipulate cellular functions with spatio-temporal precision by combining genetic engineering with the control of protein function by light. Since the discovery of channelrhodopsin has pioneered the field, the optogenetic toolkit has been ever expanding and allows now not only to control neuronal activity by light, but rather a multitude of other cellular functions. One important application that has been established in recent years is the light-dependent control of second messenger signaling. The optogenetic toolkit now allows to control cyclic nucleotide-dependent signaling by light in vitro and in vivo.},
url = {https://hdl.handle.net/20.500.11811/9772}
}
author = {{Vera Jansen} and {Jan F. Jikeli} and {Dagmar Wachten}},
title = {How to control cyclic nucleotide signaling by light},
publisher = {Amsterdam},
year = 2017,
month = mar,
journal = {Current Opinion in Biotechnology},
volume = 2017, 48,
pages = 15--20,
note = {Optogenetics allows to non-invasively manipulate cellular functions with spatio-temporal precision by combining genetic engineering with the control of protein function by light. Since the discovery of channelrhodopsin has pioneered the field, the optogenetic toolkit has been ever expanding and allows now not only to control neuronal activity by light, but rather a multitude of other cellular functions. One important application that has been established in recent years is the light-dependent control of second messenger signaling. The optogenetic toolkit now allows to control cyclic nucleotide-dependent signaling by light in vitro and in vivo.},
url = {https://hdl.handle.net/20.500.11811/9772}
}
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