E-Dissertationen: Browsing E-Dissertationen by Title
Now showing items 1809-1828 of 4074
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In vivo Relevant Drug Product Evaluation by Using the Biphasic Dissolution Assay (BiPHa+)
Denninger, Alexander Peter (2022-06-13)An increasing number of new chemical entities struggled with a very poor solubility in aqueous media. Solubility or the ability to dissolve in intestinal media is obligatory for oral bioavailability. Dealing with this ... -
In-situ characterization of self-assembled organic layers at anion modified metal/electrolyte interfaces
Phan, Thanh Hai (2013-08-22)The self-assembly of molecular layers has become an important strategy in modern design of functional materials. The sheer unlimited “design” of the properties of the organic molecules and their well controlled deposition ... -
Inclusive and differential cross-section measurements of tW single top-quark production at √s = 13 TeV with the ATLAS detector
Zhang, Rui (2019-06-27)This thesis presents the inclusive cross-section measurement and so far the first differential cross-section measurement for the associated production of a top quark and a W boson, known as the tW-channel, at 13TeV. The ... -
Independence in Algebraic Complexity Theory
Mittmann, Johannes (2013-12-16)This thesis examines the concepts of linear and algebraic independence in algebraic complexity theory. Arithmetic circuits, computing multivariate polynomials over a field, form the framework of our complexity considerations. ... -
Indexe auf verschlüsselten Daten: Konzepte, Performanz, Sicherheitsaspekte
Lehnhardt, Jan (2019-05-02)Diese Dissertation befasst sich mit Informationssystemen mit nicht vertrauenswürdiger Serverseite. Für solche Systeme bietet sich eine clientseitige Verschlüsselung ihrer Daten an, um hohe Anforderungen an deren Vertraulichkeit ... -
Indirect probes to constrain the CP nature of the Higgs boson
Klingl, Tobias (2021-08-09)The measurements of the coupling, spin, and charge-parity CP properties of the Higgs boson are consistent with the Standard Model (SM) predictions. However, the corresponding uncertainties are still large, and alternative ... -
Induktion von Immunantworten durch Immunisierung mit Fusionsproteinen aus Sequenzen der Invarianten Kette und des Hühnereiweißlysozyms
Schneiders, Angelika Maria (2003)Die Präsentation von Antigenen ist eine wichtige Voraussetzung, um Immunzellen zu aktivieren. T-Zellen erkennen Antigene als Peptide, die von Molekülen des Haupthistokompatibilitätskomplexes (MHC) auf der Zelloberfläche ... -
Inferring complex networks from time series of dynamical systems: Pitfalls, misinterpretations, and possible solutions
Bialonski, Stephan (2012-07-26)Understanding the dynamics of spatially extended systems represents a challenge in diverse scientific disciplines, ranging from physics and mathematics to the earth and climate sciences or the neurosciences. This challenge ... -
Infinitesimal analysis of singular stochastic partial differential equations
Turra, Mattia (2023-05-10)The last decade has seen a considerable rise in the study of singular stochastic partial differential equations (SPDEs) which turned into the birth of many celebrated techniques for the development of a solution theory for ... -
Inflation and Dark Matter Primordial Black Holes
Erfani, Encieh (2012-09-26)In this thesis a broad range of single field models of inflation are analyzed in light of all relevant recent cosmological data, checking whether they can lead to the formation of long--lived Primordial Black Holes (PBHs) ... -
Influence of altered gravity on the oxidative burst in macrophages
Brungs, Sonja (2013-12-10)The recognition of pathogen patterns followed by the production of reactive oxygen species (ROS) during oxidative burst is one of the major functions in macrophages. This process is the first line of defence which is crucial ... -
Influence of cyclic mechanical strain on tissues of the central nervous system
Abraham, Jella-Andrea (2020-12-17)Although the brain is the softest tissue of the human body, cells embedded in the brain are responding to physiological mechanical cues. Tissue homeostasis is, therefore, not only dependent on chemical cues (e.g. growth ... -
The influence of disorder in metallic photonic crystals
Nau, Dietmar (2006)This thesis provides a comprehensive analysis of the influence of disorder on the optical properties of metallic photonic crystal slabs. These artificial crystals consist of metallic nanowires that are arranged on top of ... -
Influence of disulfide-bonds on structural and functional properties of peptides and proteins - Case studies on FXIIIa inhibitor tridegin and µ-conotoxin PIIIA
Schmitz, Thomas (2021-05-28)Disulfide-bonded peptides have been studied for many decades serving as tools to investigate various biochemical pathways as well as lead structures for drug development for numerous diseases. Among these, the most fatal ... -
The influence of environmental UVB radiation on growth, immunity, behavior and sexually selected traits in the three-spined stickleback (Gasterosteus aculeatus)
Vitt, Simon (2020-07-13)Changing photic conditions are, next to global warming, the major aspect in terms of ongoing global climate change and mainly occur within the short-wave and high-energetic ultraviolet-B (UVB) part of the electromagnetic ... -
The influence of G-quadruplex structures on meiosis
Schwindt, Eike (2021-01-27)Several lines of evidence emphasize the potential function of G-quadruplex (G4) structures during DNA replication, transcription and recombination. Although there are experimental evidences that G4s play a role during ... -
The influence of gut-derived bacteria on systemic adaptive immune responses
Schwandt, Timo (2010-10-07)Sepsis and sepsis-associated multi-organ failure are major challenges for clinicians and scientists and are characterized by high patient morbidity and mortality. One factor thought to be important in the etiology of ... -
Influence of High-Pressure Compaction of Binary Mixtures on Solubility, Dissolution and Wettability of Borderline Poorly Soluble Drugs Employing Standard Excipients
Ibraheem, Bashar (2021-12-14)Many of new drug candidates are impaired by low aqueous solubility and slow dissolution rates, which may hinder their pharmacological response. Therefore, there is an increasing need to investigate and implement new ... -
The influence of hypoxia on RIG-I-mediated melanoma immunotherapy
Engel, Christina (2016-11-29)Hypoxia, being the inadequate tissue supply of oxygen, is a characteristic of many solid tumors that has negative implications for the patient’s prognosis. Cancer cells adapt to this hostile microenvironment by inducing ... -
The influence of ischemic pre-conditioning and inhibition of the ubiquitin proteasome system on cardiac ischemic injury in a murine model
Ayub, Muhammad Ajmal (2019-04-30)Myocardial infarction (MI) is a state when the flow of blood stops in a coronary artery or a succeeding vessel resulting in hypoxia leading to damage in the downstream cardiac tissue. Ischemia/reperfusion (I/R) injury leads ...