E-Dissertationen: Browsing E-Dissertationen by Author "Kandt, Christian"
Now showing items 1-3 of 3
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Computational Studies of the Escherichia coli Multidrug Efflux Pump AcrAB-TolC
Schmidt, Thomas H. (2014-09-05)When it was known that special substances were able to kill microbes, it was observed that some organisms were unaffected by normally lethal doses. During the last decades, the excessive usage of antibiotics has led to ... -
Coupling of Proton Transfer and Multidrug Expulsion in the Inner Membrane Translocase AcrB
Fischer, Nadine (2013-07-24)With the introduction of the first antibiotics in the 1940s, lethal bacterial infections like tuberculosis or pulmonary inflammation were widely believed to be defeated. However, bacteria inherently hold a variety of ... -
Molecular Dynamics Simulations of the Bacterial Outer Membrane Channels TolC and OprM & dxTuber, a Biomolecular Cavity Detection Tool based on Protein and Solvent Dynamics
Raunest, Martin (2013-09-12)The multidrug resistance of bacteria is a serious phenomenon in current medical treatment. Beginning with the introduction of antibiotics more and more bacterial strains achieved resistance against these chemical compounds ...