E-Dissertationen: Search
Now showing items 51-60 of 290
Diversity of regulatory systems and their contribution to colistin and tigecycline resistance in Acinetobacter baumannii
(2021-12-06)
Acinetobacter baumannii is a nosocomial pathogen which causes a wide range of serious infections in critically ill patients in the intensive care unit. Besides its high desiccation tolerance, the ability to form biofilms, ......
SRPK2 regulates active zone ultrastructure and RIM1 phosphorylation to tune presynaptic function and plasticity
(2020-07-30)
Chemical synapses communicate through the release of neurotransmitter-filled synaptic vesicles into the synaptic cleft. Synapses are able to dynamically adapt to the changes in the neuronal network by strengthening or ...
The role of the endocannabinoid system in stress-related disorders and neuroimmune communication
(2020-05-04)
In the last decades, increasing evidence suggests that inflammatory processes play an important role in the development of psychiatric disorders, such as anxiety and depression. Psychosocial stress – one of the main ...
Investigating the neural circuitry of the Mushroom body calyx in Drosophila melanogaster
(2020-07-15)
In Drosophila melanogaster, the mushroom body (MB) is essential for the formation and retrieval of olfactory associative memories. Within its input region, the MB calyx, olfactory information is delivered from second order ...
Effect of osmotic stress on barley leaf cuticles
(2021-07-19)
Assessing the drought stress tolerance at the seedling stage is an important trait as it later affects the growth and grain yield. The leaf and root characteristics are mainly focused on during this seedling stage. The ...
Propagation of Tau pathology in Alzheimer disease
(2020-09-10)
Clinical and experimental evidences suggest that the spreading of tau protein throughout the brain may underlie the stereotypical progression of pathology in the brains of Alzheimer disease (AD) patients and concomitant ...
Metabarcoding Invertebrate Communities in a Natural Park: From Methods to Diversity Patterns
(2021-02-22)
Biodiversity is worldwide suffering from a dramatic decline, whose underlying causes are still fairly unknown. The scientific investigation and identification of potential drivers of biodiversity loss are strongly hampered ...
Acetylcholine mediates protective immune responses against the rodent filarial nematode Litomosoides sigmodontis
(2022-02-22)
Tropical infectious diseases are caused by parasitic helminths, such as lymphatic filariasis and onchocerciasis (river blindness). Filariae have the ability to modulate the immune response of their host in order to be ......
Characterization of small molecule inhibitors of the NLRP3 inflammasome
(2021-08-04)
To respond quickly to infection, the innate immune system contains many germline encoded pattern recognition receptors (PRRs) that recognize a myriad of danger signals released by pathogens and damaged tissues. NLRP3 ...
GPR183 Expression on Pulmonary Conventional Dendritic Cell Type 2 Dictates Subtissular Localisation and Instructs Their Survival via the Thymic Stromal Lymphopoietin (TSLP) – TSLP Receptor (TSLPR) Axis
(2021-07-06)
Introduction: G protein-coupled receptor 183 (GPR183) is a chemotactic receptor, highly expressed by immune cells. Upon activation by its ligand, 7a,25-dihydroxycholesterol (7a,25-OHC), GPR183 activates downstream signals ......